Hajek, Andre ORCID: 0000-0002-6886-2745, Brettschneider, Christian ORCID: 0000-0002-5280-1075, Ernst, Annette, Lange, Carolin, Wiese, Birgitt, Prokein, Jana, Weyerer, Siegfried, Werle, Jochen, Pentzek, Michael, Fuchs, Angela, Stein, Janine, Bickel, Horst, Moesch, Edelgard, Heser, Kathrin, Jessen, Frank, Maier, Wolfgang, Scherer, Martin, Riedel-Heller, Steffi G. and Konig, Hans-Helmut ORCID: 0000-0001-5711-6862 (2015). Complex coevolution of depression and health-related quality of life in old age. Qual. Life Res., 24 (11). S. 2713 - 2723. DORDRECHT: SPRINGER. ISSN 1573-2649

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Abstract

Purpose To investigate the coevolution of depression and health-related quality of life (HRQoL) in old age. Methods In a representative survey of the German general population aged 75 years and older, the course of HRQoL and depression was observed over 4.5 years (3 waves). HRQoL was assessed by the Visual Analogue Scale (EQ VAS) of the EQ-5D instrument, while the Geriatric Depression Scale was used to measure depression. A panel vector autoregressive model was used to account for the complex coevolution of depression and HRQoL. Unobserved heterogeneity was taken into account by taking the first differences. Results We revealed a robust negative association between an initial change in HRQoL and a subsequent change in depression score, with substantial sex differences: In women there was a robust association, while in men the significance of this association depended on the model specification. Surprisingly, in the total sample and in both sexes, no robust association between an initial increase in depression and a subsequent change in HRQoL was found. Conclusions Findings indicate that the direction of evolution from HRQoL to depression deserves more attention. Furthermore, treatment of depression in late life should aim at improving HRQoL in which remission of depressive symptoms is necessary but not sufficient.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Hajek, AndreUNSPECIFIEDorcid.org/0000-0002-6886-2745UNSPECIFIED
Brettschneider, ChristianUNSPECIFIEDorcid.org/0000-0002-5280-1075UNSPECIFIED
Ernst, AnnetteUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lange, CarolinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wiese, BirgittUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Prokein, JanaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Weyerer, SiegfriedUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Werle, JochenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pentzek, MichaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fuchs, AngelaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stein, JanineUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bickel, HorstUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Moesch, EdelgardUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Heser, KathrinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jessen, FrankUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Maier, WolfgangUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Scherer, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Riedel-Heller, Steffi G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Konig, Hans-HelmutUNSPECIFIEDorcid.org/0000-0001-5711-6862UNSPECIFIED
URN: urn:nbn:de:hbz:38-389056
DOI: 10.1007/s11136-015-1005-8
Journal or Publication Title: Qual. Life Res.
Volume: 24
Number: 11
Page Range: S. 2713 - 2723
Date: 2015
Publisher: SPRINGER
Place of Publication: DORDRECHT
ISSN: 1573-2649
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
PRIMARY-CARE PATIENTS; BREAST-CANCER; COGNITIVE IMPAIRMENT; RISK-FACTORS; DISABILITY; ILLNESS; WOMEN; ASSOCIATION; PREVALENCE; MORTALITYMultiple languages
Health Care Sciences & Services; Health Policy & Services; Public, Environmental & Occupational HealthMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/38905

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