Universität zu Köln

Roth, Gerhard and Walkowiak, Wolfgang (2015). The Influence of Genome and Cell Size on Brain Morphology in Amphibians. Cold Spring Harbor Perspect. Biol., 7 (9). COLD SPRING HARBOR: COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT. ISSN 1943-0264

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Abstract

In amphibians, nerve cell size is highly correlated with genome size, and increases in genome and cell size cause a retardation of the rate of development of nervous (as well as nonnervous) tissue leading to secondary simplification. This yields an inverse relationship between genome and cell size on the one hand and morphological complexity of the tectum mesencephali as the main visual center, the size of the torus semicircularis as the main auditory center, the size of the amphibian papilla as an important peripheral auditory structure, and the size of the cerebellum as a major sensorimotor center. Nervous structures developing later (e.g., torus and cerebellum) are more affected by secondary simplification than those that develop earlier (e.g., the tectum). This effect is more prominent in salamanders and caecilians than in frogs owing to larger genome and cells sizes in the former two taxa. We hypothesize that because of intragenomic evolutionary processes, important differences in brain morphology can arise independently of specific environmental selection.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Roth, Gerhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Walkowiak, Wolfgang UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-393674
DOI:	10.1101/cshperspect.a019075
Journal or Publication Title:	Cold Spring Harbor Perspect. Biol.
Volume:	7
Number:	9
Date:	2015
Publisher:	COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
Place of Publication:	COLD SPRING HARBOR
ISSN:	1943-0264
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PLETHODONTID SALAMANDERS; TORUS SEMICIRCULARIS; AUDITORY MIDBRAIN; MOTOR NUCLEI; GRASS FROG; EVOLUTION; ORGANIZATION; COMPLEXITY; NEURONS; ANURA Multiple languages Cell Biology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/39367