Universität zu Köln

Schennach, R., Riedel, M., Obermeier, M., Seemueller, F., Jaeger, M., Schmauss, M., Laux, G., Pfeiffer, H., Naber, D., Schmidt, L. G., Gaebel, W., Klosterkoetter, J., Heuser, I., Maier, W., Lemke, M. R., Ruether, E., Klingberg, S., Gastpar, M. and Moeller, H. -J. (2015). What are depressive symptoms in acutely ill patients with schizophrenia spectrum disorder? Eur. Psychiat., 30 (1). PARIS: ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER. ISSN 1778-3585

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Abstract

Background: Aim was to examine depressive symptoms in acutely ill schizophrenia patients on a single symptom basis and to evaluate their relationship with positive, negative and general psychopathological symptoms. Methods: Two hundred and seventy-eight patients suffering from a schizophrenia spectrum disorder were analysed within a naturalistic study by the German Research Network on Schizophrenia. Using the Calgary Depression Scale for Schizophrenia (CDSS) depressive symptoms were examined and the Positive and Negative Syndrome Scale (PANSS) was applied to assess positive, negative and general symptoms. Correlation and factor analyses were calculated to detect the underlying structure and relationship of the patient's symptoms. Results: The most prevalent depressive symptoms identified were depressed mood (80%), observed depression (62%) and hopelessness (54%). Thirty-nine percent of the patients suffered from depressive symptoms when applying the recommended cut-off of a CDSS total score of >6 points at admission. Negligible correlations were found between depressive and positive symptoms as well as most PANSS negative and global symptoms despite items on depression, guilt and social withdrawal. The factor analysis revealed that the factor loading with the PANSS negative items accounted for most of the data variance followed by a factor with positive symptoms and three depression-associated factors. Limitations: The naturalistic study design does not allow a sufficient control of study results for the effect of different pharmacological treatments possibly influencing the appearance of depressive symptoms. Conclusion: Results suggest that depressive symptoms measured with the CDSS are a discrete symptom domain with only partial overlap with positive or negative symptoms. (C) 2014 Elsevier Masson SAS. All rights reserved.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schennach, R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Riedel, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Obermeier, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Seemueller, F. UNSPECIFIED UNSPECIFIED UNSPECIFIED Jaeger, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmauss, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Laux, G. UNSPECIFIED UNSPECIFIED UNSPECIFIED Pfeiffer, H. UNSPECIFIED UNSPECIFIED UNSPECIFIED Naber, D. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmidt, L. G. UNSPECIFIED UNSPECIFIED UNSPECIFIED Gaebel, W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Klosterkoetter, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Heuser, I. UNSPECIFIED UNSPECIFIED UNSPECIFIED Maier, W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Lemke, M. R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Ruether, E. UNSPECIFIED UNSPECIFIED UNSPECIFIED Klingberg, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Gastpar, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Moeller, H. -J. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-418799
DOI:	10.1016/j.eurpsy.2014.11.001
Journal or Publication Title:	Eur. Psychiat.
Volume:	30
Number:	1
Date:	2015
Publisher:	ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
Place of Publication:	PARIS
ISSN:	1778-3585
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language NEGATIVE SYNDROME SCALE; SCHIZOAFFECTIVE DISORDER; CLINICAL CHARACTERISTICS; PSYCHOTIC DEPRESSION; OLDER OUTPATIENTS; RATING-SCALE; MOOD; HALLUCINATIONS; VALIDITY; EPISODE Multiple languages Psychiatry Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/41879