Universität zu Köln

Ireland, Alex ORCID: 0000-0003-1094-9183, Rittweger, Joern, Schoenau, Eckhard, Lamberg-Allardt, Christel ORCID: 0000-0001-7326-1904 and Viljakainen, Hell (2014). Time since onset of walking predicts tibial bone strength in early childhood. Bone, 68. S. 76 - 85. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1873-2763

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Abstract

Bone strength in adulthood is known to be affected by health at birth and early childhood. Habitual bone loading is a primary determinant of bone strength in later childhood and adulthood. However, the effects of physical activity in early childhood (e.g. crawling, standing and walking) on bone strength are unknown. Fifty-three children (twenty-seven males) were included in a longitudinal study in their early infancy. Shortly after birth (0.3 +/- 0.3 months), details of mass and height were obtained along with a pQCT scan at 20% distal-proximal tibia length. At 14.8 +/- 0.5 months of age the same data were collected, along with details of age at onset of standing, crawling, supported and unsupported walking. Time since onset of walking unsupported was associated with greater bone mass, cortical bone area, pericortical circumference and polar moment of inertia of both total and cortical bone (all P < 0.05). There were no significant associations between other physical activity timepoints and bone measures. Age at onset of walking was not significantly related to mass, length or bone measures at birth. The results suggest that time since attainment of independent walking representing exposure of the tibia to the large reaction and muscular forces associated with locomotion is a primary determinant of bone strength in early childhood. This finding raises the possible opportunity of physical activity interventions at young age in paediatric populations associated with low childhood bone strength and late walking (e.g. low birth weight, cerebral palsy and Down's Syndrome, etc.). (C) 2014 Elsevier Inc. All rights reserved.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Ireland, Alex UNSPECIFIED orcid.org/0000-0003-1094-9183 UNSPECIFIED Rittweger, Joern UNSPECIFIED UNSPECIFIED UNSPECIFIED Schoenau, Eckhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Lamberg-Allardt, Christel UNSPECIFIED orcid.org/0000-0001-7326-1904 UNSPECIFIED Viljakainen, Hell UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-424943
DOI:	10.1016/j.bone.2014.08.003
Journal or Publication Title:	Bone
Volume:	68
Page Range:	S. 76 - 85
Date:	2014
Publisher:	ELSEVIER SCIENCE INC
Place of Publication:	NEW YORK
ISSN:	1873-2763
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language QUANTITATIVE COMPUTED-TOMOGRAPHY; PHYSICAL-ACTIVITY; MINERAL STATUS; DOWN-SYNDROME; NEWBORN-INFANTS; CEREBRAL-PALSY; TERM INFANTS; BIRTH-WEIGHT; WHOLE-BODY; MASS Multiple languages Endocrinology & Metabolism Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/42494