Universität zu Köln

Mueller, Dirk, Schaeffeler, Christoph, Baum, Thomas ORCID: 0000-0002-4574-5212, Walter, Flavia, Rechl, Hans, Rummeny, Ernst J. and Woertler, Klaus (2014). Magnetic resonance perfusion and diffusion imaging characteristics of transient bone marrow edema, avascular necrosis and subchondral insufficiency fractures of the proximal femur. Eur. J. Radiol., 83 (10). S. 1862 - 1870. CLARE: ELSEVIER IRELAND LTD. ISSN 1872-7727

Full text not available from this repository.

Abstract

Purpose: To evaluate magnetic resonance (MR) perfusion and diffusion imaging characteristics in patients with transient bone marrow edema (TBME), avascular necrosis (AVN), or subchondral insufficiency fractures (SIF) of the proximal femur. Materials and methods: 29 patients with painful hip and bone marrow edema pattern of the proximal femur on non-contrast MR imaging were examined using diffusion-weighted and dynamic gadolinium-enhanced sequences. Apparent diffusion coefficients (ADCs) and perfusion parameters were calculated for different regions of the proximal femur. Regional distribution and differences in ADC values and perfusion parameters were evaluated. Results: Seven patients presented with TBME, 15 with AVN and seven with SIF of the proximal femur. Perfusion imaging showed significant differences for maximum enhancement values (E-max), slope (E-slope) and time to peak (TTP) between the three patient groups (p < 0.05). In contrast, no significant differences for ADC values were calculated when comparing TBME, AVN, and SIF patients. Conclusion: Diffusion weighted imaging of bone marrow of the proximal femur did not show significant differences between patients with TBME, AVN or SIF. In contrast, MR perfusion imaging demonstrated significant differences for the different patient groups and may as a complementary imaging technique add information to the understanding of the pathophysiology of diseases associated with bone marrow edema. (C) 2014 Elsevier Ireland Ltd. All rights reserved.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Mueller, Dirk UNSPECIFIED UNSPECIFIED UNSPECIFIED Schaeffeler, Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED Baum, Thomas UNSPECIFIED orcid.org/0000-0002-4574-5212 UNSPECIFIED Walter, Flavia UNSPECIFIED UNSPECIFIED UNSPECIFIED Rechl, Hans UNSPECIFIED UNSPECIFIED UNSPECIFIED Rummeny, Ernst J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Woertler, Klaus UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-427977
DOI:	10.1016/j.ejrad.2014.07.017
Journal or Publication Title:	Eur. J. Radiol.
Volume:	83
Number:	10
Page Range:	S. 1862 - 1870
Date:	2014
Publisher:	ELSEVIER IRELAND LTD
Place of Publication:	CLARE
ISSN:	1872-7727
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language FEMORAL-HEAD; MR; OSTEONECROSIS; OSTEOPOROSIS; HIP; LESIONS; JOINT; MODEL Multiple languages Radiology, Nuclear Medicine & Medical Imaging Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/42797