Eckes, Beate, Moinzadeh, Pia, Sengle, Gerhard, Hunzelmann, Nico and Krieg, Thomas (2014). Molecular and cellular basis of scleroderma. J. Mol. Med., 92 (9). S. 913 - 925. NEW YORK: SPRINGER. ISSN 1432-1440
Full text not available from this repository.Abstract
Systemic sclerosis (scleroderma) is a chronic inflammatory disease that leads to fibrosis of the skin and involved internal organs. No efficient therapy is currently available. This review summarizes recent progress made in basic as well as clinical science and concludes with a concept that therapy targeting fibrosis in scleroderma needs to take into account the global microenvironment in the skin with its diverse cellular players interacting with a complex extracellular matrix environment and matrix-associated growth factors.
Item Type: | Journal Article | ||||||||||||||||||||||||
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URN: | urn:nbn:de:hbz:38-430645 | ||||||||||||||||||||||||
DOI: | 10.1007/s00109-014-1190-x | ||||||||||||||||||||||||
Journal or Publication Title: | J. Mol. Med. | ||||||||||||||||||||||||
Volume: | 92 | ||||||||||||||||||||||||
Number: | 9 | ||||||||||||||||||||||||
Page Range: | S. 913 - 925 | ||||||||||||||||||||||||
Date: | 2014 | ||||||||||||||||||||||||
Publisher: | SPRINGER | ||||||||||||||||||||||||
Place of Publication: | NEW YORK | ||||||||||||||||||||||||
ISSN: | 1432-1440 | ||||||||||||||||||||||||
Language: | English | ||||||||||||||||||||||||
Faculty: | Unspecified | ||||||||||||||||||||||||
Divisions: | Unspecified | ||||||||||||||||||||||||
Subjects: | no entry | ||||||||||||||||||||||||
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URI: | http://kups.ub.uni-koeln.de/id/eprint/43064 |
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