Universität zu Köln

Schier, Robert, Schick, Volker, Amsbaugh, Ashley, Aguilar, Jorge, Hernandez, Mike, Mehran, Reza J., Riedel, Bernhard and Hinkelbein, Jochen (2014). Brachial artery reactivity and vascular reactive hyperemia for preoperative anaesthesia risk assessment - an observational study. BMC Anesthesiol., 14. LONDON: BMC. ISSN 1471-2253

Full text not available from this repository.

Abstract

Background: Non-invasive measures of vascular reactivity have emerged to refine cardiovascular risk. However, limited data exists investigating vascular reactivity as a preoperative diagnostic tool for anesthesiologists. In this study, we compare the utility of two non-invasive techniques, Brachial Artery Reactivity Testing (BART) and Digital Thermal Monitoring (DTM), as surrogates for measuring vascular reactivity. Methods: Following IRB approval, 26 patients scheduled for major thoracic surgery (e. g. esophagectomy and pneumonectomy) were studied prospectively. BART [Flow mediated dilation (FMD) and Peak flow velocity (PFV)] and DTM [Temperature rebound (TR%)] were performed preoperatively at baseline using 5 minute blood pressure cuff occlusion of the upper arm. Statistical summaries were provided for the comparison of BART and DTM with select patient characteristics, and correlations were used to investigate the strength of the relationship between BART and DTM measurements. Results: Patients preoperatively diagnosed with hyperlipidemia were associated with lower FMD% values {Median (Range): 14.8 (2.3, 38.1) vs. 6.2 (0.0, 14.3); p = 0.006}. There were no significant associations between BART and DTM techniques in relation to cardiovascular risk factors or postoperative complications. Conclusion: Our study suggests that impaired vascular reactivity as measured by BART is associated with the incidence of hyperlipidemia. Also, using a novel technique such as DTM may provide a simpler and more accessible point of care testing for vascular reactivity in a perioperative setting. Both non-invasive techniques assessing vascular function warrant further refinement to better assist preoperative optimization strategies aimed at improving perioperative vascular function.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schier, Robert UNSPECIFIED UNSPECIFIED UNSPECIFIED Schick, Volker UNSPECIFIED UNSPECIFIED UNSPECIFIED Amsbaugh, Ashley UNSPECIFIED UNSPECIFIED UNSPECIFIED Aguilar, Jorge UNSPECIFIED UNSPECIFIED UNSPECIFIED Hernandez, Mike UNSPECIFIED UNSPECIFIED UNSPECIFIED Mehran, Reza J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Riedel, Bernhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Hinkelbein, Jochen UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-435668
DOI:	10.1186/1471-2253-14-47
Journal or Publication Title:	BMC Anesthesiol.
Volume:	14
Date:	2014
Publisher:	BMC
Place of Publication:	LONDON
ISSN:	1471-2253
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ENDOTHELIUM-DEPENDENT DILATION; NONINVASIVE DETECTION; DYSFUNCTION; TOOL; PREVENTION; RESISTANCE; SMOKING; BLOOD; FLOW Multiple languages Anesthesiology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/43566