Universität zu Köln

Lier, H. and Hinkelbein, J. (2014). Coagulation therapy in multiple trauma without point-of-care testing. Unfallchirurg, 117 (2). S. 105 - 111. NEW YORK: SPRINGER. ISSN 1433-044X

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Abstract

Analysis of blood coagulation with thrombelastometry (ROTEM (TM)) and thrombelastography (TEG (TM)) and analysis of thrombocyte function by a Multiplate (TM) assay is possible in only a few hospitals in Germany. Recently, the grade of recommendation (GoR) for point-of-care (POC) testing in official guidelines was increased and is now classified as GoR 1C. If a POC-based option is not available alternatives must be used. Besides blood products (RBC, FFP, TC), coagulation factor concentrates are used to treat trauma-induced coagulopathy. The benefits of therapy with factor concentrates are fewer immunological and infection side effects as well as faster effects after administration of specific coagulation factors. A good outcome in patients with multiple trauma is only possible by an adequate transfusion regime and administration of coagulation factors.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Lier, H. UNSPECIFIED UNSPECIFIED UNSPECIFIED Hinkelbein, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-446942
DOI:	10.1007/s00113-013-2491-1
Journal or Publication Title:	Unfallchirurg
Volume:	117
Number:	2
Page Range:	S. 105 - 111
Date:	2014
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1433-044X
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language MANAGEMENT; SOCIETY; RECOMMENDATIONS; ANESTHESIOLOGY; HYPOCALCEMIA; GUIDELINES Multiple languages Emergency Medicine; Surgery Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/44694