Malter, Wolfram, Kirn, Verena, Mallmann, Peter and Kraemer, Stefan (2014). Oncoplastic breast reconstruction after IORT. Transl. Cancer Res., 3 (1). S. 74 - 83. SHATIN: AME PUBL CO. ISSN 2219-6803
Full text not available from this repository.Abstract
Prospective randomized clinical trials have shown that breast-conserving surgery followed by radiotherapy gives equivalent survival rates compared with mastectomy. The indications for breast-conserving therapy in breast cancer are expanding. The integration of oncoplastic surgery techniques with breast-conserving segmentectomy is a new approach that allows more extensive resections and results in more cosmetic favourable outcomes. During the last years we have defined five reconstruction principles in oncoplastic breast-conserving surgery. With these five principles we were able to perform more than 95% of all immediate reconstructions of partial mastectomy defects during breast-conserving surgery, resulting in optimized local and aesthetic outcomes. The oncoplastic reconstruction principles of partial mastectomy defects during breast-conserving surgery are as follows: glandular rotation, dermoglandular rotation, tumoradapted reduction mammoplasty, thoracoepigastric flap, Latissimus dorsi flap. Usually the whole breast is percutaneously irradiated after breast-conserving surgery. Depending on different risk factors, a local boost dose is applied to the tumor bed, which leads to a further reduction of local recurrences. Recently, the concept of intraoperative radiotherapy (IORT) as boost during breast-conserving surgery has been introduced internationally. From a surgical point of view intraoperative boost radiotherapy with a mobile device generating low-energy X-rays (Intrabeam (R)) can be combined with all oncoplastic principles for reconstructing partial mastectomy defects. The advantage of an oncoplastic reconstruction after breast-onserving surgery and IORT boost irradiation should be recommended to improve local outcome, to avoid seroma formation and to improve the cosmetic outcome after treatment.
Item Type: | Journal Article | ||||||||||||||||||||
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URN: | urn:nbn:de:hbz:38-447932 | ||||||||||||||||||||
DOI: | 10.3978/j.issn.2218-676X.2014.01.04 | ||||||||||||||||||||
Journal or Publication Title: | Transl. Cancer Res. | ||||||||||||||||||||
Volume: | 3 | ||||||||||||||||||||
Number: | 1 | ||||||||||||||||||||
Page Range: | S. 74 - 83 | ||||||||||||||||||||
Date: | 2014 | ||||||||||||||||||||
Publisher: | AME PUBL CO | ||||||||||||||||||||
Place of Publication: | SHATIN | ||||||||||||||||||||
ISSN: | 2219-6803 | ||||||||||||||||||||
Language: | English | ||||||||||||||||||||
Faculty: | Unspecified | ||||||||||||||||||||
Divisions: | Unspecified | ||||||||||||||||||||
Subjects: | no entry | ||||||||||||||||||||
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URI: | http://kups.ub.uni-koeln.de/id/eprint/44793 |
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