Universität zu Köln

Malter, Wolfram, Kirn, Verena, Mallmann, Peter and Kraemer, Stefan (2014). Oncoplastic breast reconstruction after IORT. Transl. Cancer Res., 3 (1). S. 74 - 83. SHATIN: AME PUBL CO. ISSN 2219-6803

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Abstract

Prospective randomized clinical trials have shown that breast-conserving surgery followed by radiotherapy gives equivalent survival rates compared with mastectomy. The indications for breast-conserving therapy in breast cancer are expanding. The integration of oncoplastic surgery techniques with breast-conserving segmentectomy is a new approach that allows more extensive resections and results in more cosmetic favourable outcomes. During the last years we have defined five reconstruction principles in oncoplastic breast-conserving surgery. With these five principles we were able to perform more than 95% of all immediate reconstructions of partial mastectomy defects during breast-conserving surgery, resulting in optimized local and aesthetic outcomes. The oncoplastic reconstruction principles of partial mastectomy defects during breast-conserving surgery are as follows: glandular rotation, dermoglandular rotation, tumoradapted reduction mammoplasty, thoracoepigastric flap, Latissimus dorsi flap. Usually the whole breast is percutaneously irradiated after breast-conserving surgery. Depending on different risk factors, a local boost dose is applied to the tumor bed, which leads to a further reduction of local recurrences. Recently, the concept of intraoperative radiotherapy (IORT) as boost during breast-conserving surgery has been introduced internationally. From a surgical point of view intraoperative boost radiotherapy with a mobile device generating low-energy X-rays (Intrabeam (R)) can be combined with all oncoplastic principles for reconstructing partial mastectomy defects. The advantage of an oncoplastic reconstruction after breast-onserving surgery and IORT boost irradiation should be recommended to improve local outcome, to avoid seroma formation and to improve the cosmetic outcome after treatment.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Malter, Wolfram UNSPECIFIED UNSPECIFIED UNSPECIFIED Kirn, Verena UNSPECIFIED UNSPECIFIED UNSPECIFIED Mallmann, Peter UNSPECIFIED UNSPECIFIED UNSPECIFIED Kraemer, Stefan UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-447932
DOI:	10.3978/j.issn.2218-676X.2014.01.04
Journal or Publication Title:	Transl. Cancer Res.
Volume:	3
Number:	1
Page Range:	S. 74 - 83
Date:	2014
Publisher:	AME PUBL CO
Place of Publication:	SHATIN
ISSN:	2219-6803
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language 20-YEAR FOLLOW-UP; INTRAOPERATIVE RADIOTHERAPY; CONSERVING SURGERY; MASTECTOMY; CANCER; IRRADIATION; LUMPECTOMY; THERAPY; REPAIR; IMPACT Multiple languages Oncology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/44793