Universität zu Köln

Klosterkoetter, J. (2013). Prevention of psychotic disorders. Nervenarzt, 84 (11). S. 1299 - 1308. NEW YORK: SPRINGER. ISSN 1433-0407

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Abstract

Psychotic disorders set the first example that prediction and prevention programs of modern medicine can also be successfully applied to central psychiatric disorders. In the last 20 years criteria for the detection of high-risk states prior to the first onset of the disease have been worked out and the predictive power for the transition into psychosis has been confirmed. In the centers for early recognition and prevention, persons seeking help and advice can now be classified into individuals in an early or late high-risk stage by means of newly developed instruments. New possibilities of risk stratification ensure a more individualized selection of appropriate preventive measures. The interventions provided aim at improving risk symptoms, preventing psychosocial disabilities and in particular preventing or at least delaying the onset of psychosis. Proof of efficacy is so far available for newly developed psychotherapeutic methods, neuroprotective agents and low dosage antipsychotics. Prior to administration careful risk-benefit analyses have to be carried out for each individual case.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Klosterkoetter, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-472675
DOI:	10.1007/s00115-013-3831-7
Journal or Publication Title:	Nervenarzt
Volume:	84
Number:	11
Page Range:	S. 1299 - 1308
Date:	2013
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1433-0407
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language HIGH-RISK; AT-RISK; 1ST-EPISODE PSYCHOSIS; INDICATED PREVENTION; PREDICTION; SCHIZOPHRENIA; PROGRESSION; PLACEBO; TRIAL; ONSET Multiple languages Clinical Neurology; Psychiatry Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/47267