Universität zu Köln

Pagel, T., Baldessarini, R. J., Franklin, J. and Baethge, C. (2013). Heterogeneity of schizoaffective disorder compared with schizophrenia and bipolar disorder. Acta Psychiatr. Scand., 128 (4). S. 238 - 251. HOBOKEN: WILEY. ISSN 1600-0447

Full text not available from this repository.

Abstract

ObjectiveLow diagnostic reliability, the need to meet criteria of two disorders, and its status as residual diagnosis in clinical practice led us to hypothesize that schizoaffective disorder (SAD) is characterized by considerable heterogeneity, particularly in comparison with schizophrenia (SZ) and bipolar disorder (BD). As this has not been investigated the aim of this study is to test whether heterogeneity is larger in SAD than in SZ and BD. MethodSystematic search for studies simultaneously comparing all three diagnoses regarding demographic, clinical, psychometric (clinical rating scales and IQ tests), and biological parameters; comparison of heterogeneity as measured by standard deviation (SD). ResultsStandard deviation of SAD samples (N=47) was smaller than in both differential diagnoses. SDs were 7% higher in BD than in SAD (SZ: 2% higher); in studies employing DSM-IIIR/-IV pooled SD was 4% higher in BD (8% lower in SZ). Differences between diagnoses were limited to the comparison of SAD and BD, and became smaller when only psychotic BD was considered. ConclusionHeterogeneity of SZ and BD is not smaller than that of SAD. SAD seems not to be more diverse than other functional psychoses. Results are preliminary because of the novelty of the approach and to the small number of studies.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Pagel, T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Baldessarini, R. J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Franklin, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Baethge, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-474838
DOI:	10.1111/acps.12109
Journal or Publication Title:	Acta Psychiatr. Scand.
Volume:	128
Number:	4
Page Range:	S. 238 - 251
Date:	2013
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1600-0447
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language TERM-FOLLOW-UP; MOOD DISORDERS; PSYCHIATRIC-DISORDERS; PSYCHOTIC FEATURES; DIAGNOSTIC GROUPS; DSM-IV; UNIPOLAR DEPRESSION; CLINICAL-FEATURES; NEGATIVE SYMPTOMS; THOUGHT-DISORDER Multiple languages Psychiatry Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/47483