Universität zu Köln

Kornfeld, Jan-Wilhelm ORCID: 0000-0002-6802-4442 and Bruening, Jens C. (2012). MyomiRs-133a/b turn off the heat. Nat. Cell Biol., 14 (12). S. 1248 - 1250. LONDON: NATURE PUBLISHING GROUP. ISSN 1465-7392

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Abstract

Brown adipose tissue is intensively researched owing to its role in regulating energy and glucose homeostasis. Its differentiation is controlled through adrenergic-dependent regulation of the transcriptional co-regulator Prdm16. Adrenergic stimulation inhibits expression of miR-133a/b in a Mef2c-dependent manner to abrogate post-transcriptional silencing of Prdm16.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Kornfeld, Jan-Wilhelm UNSPECIFIED orcid.org/0000-0002-6802-4442 UNSPECIFIED Bruening, Jens C. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-478139
DOI:	10.1038/ncb2642
Journal or Publication Title:	Nat. Cell Biol.
Volume:	14
Number:	12
Page Range:	S. 1248 - 1250
Date:	2012
Publisher:	NATURE PUBLISHING GROUP
Place of Publication:	LONDON
ISSN:	1465-7392
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language BROWN ADIPOSE-TISSUE; MICE; FAT; ADIPOCYTES; OBESITY; DIFFERENTIATION; THERMOGENESIS; EXPRESSION; ABLATION; BEIGE Multiple languages Cell Biology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/47813