Universität zu Köln

Lippert-Gruener, Marcela (2012). Botulinum toxin in the treatment of post-traumatic headache - case study. Neurol. Neurochir. Pol., 46 (6). S. 591 - 595. POZNAN: TERMEDIA PUBLISHING HOUSE LTD. ISSN 0028-3843

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Abstract

Pharmacotherapy of acute post-traumatic tension headaches consists of analgesics and non-steroidal anti-inflammatory drugs (NSAIDs). Treatment of chronic tension-type headaches consists mainly of tricyclic antidepressants; local injection of botulinum toxin is one of the comparatively newer therapeutic options. No data on the treatment of post-traumatic headaches with botulinum toxin exist. A 62-year-old woman with a history of major traumatic brain injury five years previously developed chronic tension-type headaches of an oppressive nature. The results of treatment with oral medication were not satisfactory. The patient was treated with local injections of 22 IU Botox (R) into the frontalis muscle and corrugator supercilii muscle. After only five days, the headaches had improved and after ten days the patient was free of symptoms even when under stress. Sufficiently large-scale clinical studies are now required to better evaluate the effects of botulinum toxin on post-traumatic headaches.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Lippert-Gruener, Marcela UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-479296
DOI:	10.5114/ninp.2012.32109
Journal or Publication Title:	Neurol. Neurochir. Pol.
Volume:	46
Number:	6
Page Range:	S. 591 - 595
Date:	2012
Publisher:	TERMEDIA PUBLISHING HOUSE LTD
Place of Publication:	POZNAN
ISSN:	0028-3843
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language TENSION-TYPE HEADACHE; EPISODIC MIGRAINE HEADACHES; PLACEBO-CONTROLLED TRIAL; DOUBLE-BLIND; PROPHYLACTIC TREATMENT; CONTROLLED PHASE; PARALLEL-GROUP; A INJECTION; ONABOTULINUMTOXINA; MULTICENTER Multiple languages Clinical Neurology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/47929