Universität zu Köln

Grajewski, Rafael S., Zurek-Imhoff, Beatrix, Roesel, Martin, Heinz, Carsten and Heiligenhaus, Arnd (2012). Favourable outcome after cataract surgery with IOL implantation in uveitis associated with juvenile idiopathic arthritis. Acta Ophthalmol., 90 (7). S. 657 - 663. HOBOKEN: WILEY. ISSN 1755-3768

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Abstract

Purpose: Management of uveitic cataract in patients with juvenile idiopathic arthritis (JIA) is challenging, and intraocular lens (IOL) implantation is controversial. This study investigated the outcome after minimally invasive surgery with IOL implantation. Methods: Retrospective analysis after phacoemulsification with in-the-bag IOL implantation was performed in 16 patients (17 operations) with ANA-positive JIA-associated chronic uveitis. In these patients, 25 G capsulectomy and anterior vitrectomy was performed and they received an intravitreal triamcinolone (TA) injection. Results: Mean age at uveitis onset was 5 +/- 2 years, and surgery was performed at a mean age of 11 +/- 2.2 years. Preoperatively, uveitis was inactive in all patients, and visual acuity was logMAR 0.8 +/- 0.44; additional uveitis complications were present in all patients, and 15 patients were receiving systemic immunosuppression/biologicals. After surgery (mean follow-up 26.5 +/- 11.7 months), presence of cystoid macular oedema, papilloedema, ocular hypertension/glaucoma and hypotony did not increase compared with baseline. There was no significant worsening of AC inflammation (by cell numbers and laser flare values). IOL deposits persisted in four patients, and synechiae developed in eight. The visual acuity was improved (>= 2 lines) in all patients (mean logMAR 0.3 +/- 0.24). Retrolental membrane formation was not noted. Secondary capsular opacification was observed in seven patients, requiring Nd:YAG capsulotomy in five of them. Conclusions: Phacoemulsification and in-the-bag IOL implantation may improve visual outcome in JIA-associated uveitis with minimally invasive surgical technique and intravitreal TA injection. Well-controlled uveitis with appropriate use of topical steroids and systemic immunosuppression or biologicals appears as a perioperative requirement.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Grajewski, Rafael S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Zurek-Imhoff, Beatrix UNSPECIFIED UNSPECIFIED UNSPECIFIED Roesel, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Heinz, Carsten UNSPECIFIED UNSPECIFIED UNSPECIFIED Heiligenhaus, Arnd UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-479965
DOI:	10.1111/j.1755-3768.2011.02110.x
Journal or Publication Title:	Acta Ophthalmol.
Volume:	90
Number:	7
Page Range:	S. 657 - 663
Date:	2012
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1755-3768
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language INTRAOCULAR-LENS IMPLANTATION; TRIAMCINOLONE ACETONIDE; AQUEOUS-HUMOR; CHILDREN; PHACOEMULSIFICATION; INJECTION; EYES; PROPHYLAXIS; EFFICACY; SAFETY Multiple languages Ophthalmology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/47996