Universität zu Köln

Kreppel, Matthias, Drebber, Uta, Rothamel, Daniel, Eich, Hans-Theodor, Kuebler, Alexander, Scheer, Martin and Zoeller, Joachim E. (2011). PROGNOSTIC IMPACT OF DIFFERENT TNM-BASED STAGE GROUPINGS FOR ORAL SQUAMOUS CELL CARCINOMA. Head Neck-J. Sci. Spec. Head Neck, 33 (10). S. 1467 - 1476. HOBOKEN: WILEY. ISSN 1097-0347

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Abstract

Background. The purpose of this study was to evaluate the prognostic significance of different TNM-based stage groupings proposed in the literature. Methods. We conducted a retrospective analysis of 300 patients with primary oral squamous cell carcinoma (T1-4, N0-2, M0). The stage grouping systems of the sixth edition of the Union Internationale Contre le Cancer (UICC), T and N Integer Score (TANIS), the Snyderman scheme, the Hart scheme, and the Berg scheme were tested for their prognostic significance. Disease free survival (DFS) was plotted by Kaplan-Meier analysis. Prognostic factors were identified through univariate and multivariate analysis. Results. On univariate analysis, all systems revealed discriminatory power for DFS; however, on multivariate analysis, only the Hart scheme predicted DFS. The TANIS did not have a better prognostic ability than the UICC stage grouping. Conclusion. Unlike in previous studies, the UICC stage grouping did perform worse than other TNM-based stage groupings, which may be due to the alterations made in the sixth edition. (C) 2010 Wiley Periodicals, Inc. Head Neck 33: 1467-1475, 2011

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Kreppel, Matthias UNSPECIFIED UNSPECIFIED UNSPECIFIED Drebber, Uta UNSPECIFIED UNSPECIFIED UNSPECIFIED Rothamel, Daniel UNSPECIFIED UNSPECIFIED UNSPECIFIED Eich, Hans-Theodor UNSPECIFIED UNSPECIFIED UNSPECIFIED Kuebler, Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED Scheer, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Zoeller, Joachim E. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-488436
DOI:	10.1002/hed.21630
Journal or Publication Title:	Head Neck-J. Sci. Spec. Head Neck
Volume:	33
Number:	10
Page Range:	S. 1467 - 1476
Date:	2011
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1097-0347
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PLUS RADICAL SURGERY; NECK-CANCER; PUBLISHED HEAD; PREOPERATIVE RADIOCHEMOTHERAPY; CONCURRENT CHEMORADIOTHERAPY; ADJUVANT RADIOTHERAPY; OROPHARYNGEAL CANCER; CHEMOTHERAPY; SYSTEM; CAVITY Multiple languages Otorhinolaryngology; Surgery Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/48843