Kreppel, Matthias, Drebber, Uta, Rothamel, Daniel, Eich, Hans-Theodor, Kuebler, Alexander, Scheer, Martin and Zoeller, Joachim E. (2011). PROGNOSTIC IMPACT OF DIFFERENT TNM-BASED STAGE GROUPINGS FOR ORAL SQUAMOUS CELL CARCINOMA. Head Neck-J. Sci. Spec. Head Neck, 33 (10). S. 1467 - 1476. HOBOKEN: WILEY. ISSN 1097-0347
Full text not available from this repository.Abstract
Background. The purpose of this study was to evaluate the prognostic significance of different TNM-based stage groupings proposed in the literature. Methods. We conducted a retrospective analysis of 300 patients with primary oral squamous cell carcinoma (T1-4, N0-2, M0). The stage grouping systems of the sixth edition of the Union Internationale Contre le Cancer (UICC), T and N Integer Score (TANIS), the Snyderman scheme, the Hart scheme, and the Berg scheme were tested for their prognostic significance. Disease free survival (DFS) was plotted by Kaplan-Meier analysis. Prognostic factors were identified through univariate and multivariate analysis. Results. On univariate analysis, all systems revealed discriminatory power for DFS; however, on multivariate analysis, only the Hart scheme predicted DFS. The TANIS did not have a better prognostic ability than the UICC stage grouping. Conclusion. Unlike in previous studies, the UICC stage grouping did perform worse than other TNM-based stage groupings, which may be due to the alterations made in the sixth edition. (C) 2010 Wiley Periodicals, Inc. Head Neck 33: 1467-1475, 2011
Item Type: | Journal Article | ||||||||||||||||||||||||||||||||
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URN: | urn:nbn:de:hbz:38-488436 | ||||||||||||||||||||||||||||||||
DOI: | 10.1002/hed.21630 | ||||||||||||||||||||||||||||||||
Journal or Publication Title: | Head Neck-J. Sci. Spec. Head Neck | ||||||||||||||||||||||||||||||||
Volume: | 33 | ||||||||||||||||||||||||||||||||
Number: | 10 | ||||||||||||||||||||||||||||||||
Page Range: | S. 1467 - 1476 | ||||||||||||||||||||||||||||||||
Date: | 2011 | ||||||||||||||||||||||||||||||||
Publisher: | WILEY | ||||||||||||||||||||||||||||||||
Place of Publication: | HOBOKEN | ||||||||||||||||||||||||||||||||
ISSN: | 1097-0347 | ||||||||||||||||||||||||||||||||
Language: | English | ||||||||||||||||||||||||||||||||
Faculty: | Unspecified | ||||||||||||||||||||||||||||||||
Divisions: | Unspecified | ||||||||||||||||||||||||||||||||
Subjects: | no entry | ||||||||||||||||||||||||||||||||
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URI: | http://kups.ub.uni-koeln.de/id/eprint/48843 |
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