Universität zu Köln

Malecki, Monika, Schildgen, Verena and Schildgen, Oliver ORCID: 0000-0003-4297-9627 (2011). Human bocavirus: still more questions than answers. Future Virol., 6 (9). S. 1107 - 1115. LONDON: FUTURE MEDICINE LTD. ISSN 1746-0808

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Abstract

The human bocavirus was first detected in 2005 and since then has been found in both respiratory secretions from patients with airway infections and in stool samples from patients with gastroenteritis. Meanwhile, four different genotypes have been identified that most likely derive from recombination events. Although the modified Koch's postulates have not yet been fulfilled completely, owing to the lack of an animal model or a simple cell culture system, there is increasing evidence that the human bocaviruses are serious participants in infectious diseases of the respiratory and the GI tracts. This article reviews the current status of the clinical features of human bocaviruses and provides an overview of the latest findings concerning the biology, phylogeny, epidemiology and diagnostic tools related to human bocaviruses. Furthermore, it discusses the potential pathogenicity of human bocavirus, as well as its persistence and reactivation in hosts.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Malecki, Monika UNSPECIFIED UNSPECIFIED UNSPECIFIED Schildgen, Verena UNSPECIFIED UNSPECIFIED UNSPECIFIED Schildgen, Oliver UNSPECIFIED orcid.org/0000-0003-4297-9627 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-489409
DOI:	10.2217/FVL.11.78
Journal or Publication Title:	Future Virol.
Volume:	6
Number:	9
Page Range:	S. 1107 - 1115
Date:	2011
Publisher:	FUTURE MEDICINE LTD
Place of Publication:	LONDON
ISSN:	1746-0808
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language HUMAN PARVOVIRUS B19; REAL-TIME PCR; ACUTE GASTROENTERITIS; MINUTE VIRUS; EPIDEMIOLOGIC PROFILE; FREQUENT DETECTION; YOUNG-CHILDREN; INFECTION; PROTEIN; DNA Multiple languages Virology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/48940