Universität zu Köln

Sievers, Hans-H, Stierle, Ulrich, Charitos, Efstratios I., Hanke, Thorsten, Misfeld, Martin, Bechtel, J. F. Matthias, Gorski, Armin, Franke, Ulrich F. W., Graf, Bernhard, Robinson, Derek R., Bogers, Ad J. J. C., Dodge-Khatami, Ali, Boehm, Juergen O., Rein, Joachim G., Botha, Cornelius A., Lange, Ruediger, Hoerer, Juergen, Moritz, Anton, Wahlers, Thorsten, Breuer, Martin, Ferrari-Kuehne, Katharina ORCID: 0000-0001-8928-8538, Hetzer, Roland, Huebler, Michael, Ziemer, Gerhard, Takkenberg, Johanna J. M. and Hemmer, Wolfgang (2010). Major Adverse Cardiac and Cerebrovascular Events After the Ross Procedure A Report From the German-Dutch Ross Registry. Circulation, 122 (11). S. S216 - 8. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1524-4539

Full text not available from this repository.

Abstract

Background-The purpose of the study is to report major cardiac and cerebrovascular events after the Ross procedure in the large adult and pediatric population of the German-Dutch Ross registry. These data could provide an additional basis for discussions among physicians and a source of information for patients. Methods and Results-One thousand six hundred twenty patients (1420 adults; 1211 male; mean age, 39.2+/-16.2 years) underwent a Ross procedure between 1988 and 2008. Follow-up was performed on an annual basis (median, 6.2 years; 10 747 patient-years). Early and late mortality were 1.2% (n=19) and 3.6% (n=58; 0.54%/patient-year), respectively. Ninety-three patients underwent 99 reinterventions on the autograft (0.92%/patient-year); 78 reinterventions in 63 patients on the pulmonary conduit were performed (0.73%/patient-year). Freedom from autograft or pulmonary conduit reoperation was 98.2%, 95.1%, and 89% at 1, 5, and 10 years, respectively. Preoperative aortic regurgitation and the root replacement technique without surgical autograft reinforcement were associated with a greater hazard for autograft reoperation. Major internal or external bleeding occurred in 17 (0.15%/patient-year), and a total of 38 patients had composite end point of thrombosis, embolism, or bleeding (0.35%/patient-year). Late endocarditis with medical (n=16) or surgical treatment (n=29) was observed in 38 patients (0.38%/patient-year). Freedom from any valve-related event was 94.9% at 1 year, 90.7% at 5 years, and 82.5% at 10 years. Conclusions-Although longer follow-up of patients who undergo Ross operation is needed, the present series confirms that the autograft procedure is a valid option to treat aortic valve disease in selected patients. The nonreinforced full root technique and preoperative aortic regurgitation are predictors for autograft failure and warrant further consideration.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Sievers, Hans-H UNSPECIFIED UNSPECIFIED UNSPECIFIED Stierle, Ulrich UNSPECIFIED UNSPECIFIED UNSPECIFIED Charitos, Efstratios I. UNSPECIFIED UNSPECIFIED UNSPECIFIED Hanke, Thorsten UNSPECIFIED UNSPECIFIED UNSPECIFIED Misfeld, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Bechtel, J. F. Matthias UNSPECIFIED UNSPECIFIED UNSPECIFIED Gorski, Armin UNSPECIFIED UNSPECIFIED UNSPECIFIED Franke, Ulrich F. W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Graf, Bernhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Robinson, Derek R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Bogers, Ad J. J. C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Dodge-Khatami, Ali UNSPECIFIED UNSPECIFIED UNSPECIFIED Boehm, Juergen O. UNSPECIFIED UNSPECIFIED UNSPECIFIED Rein, Joachim G. UNSPECIFIED UNSPECIFIED UNSPECIFIED Botha, Cornelius A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Lange, Ruediger UNSPECIFIED UNSPECIFIED UNSPECIFIED Hoerer, Juergen UNSPECIFIED UNSPECIFIED UNSPECIFIED Moritz, Anton UNSPECIFIED UNSPECIFIED UNSPECIFIED Wahlers, Thorsten UNSPECIFIED UNSPECIFIED UNSPECIFIED Breuer, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Ferrari-Kuehne, Katharina UNSPECIFIED orcid.org/0000-0001-8928-8538 UNSPECIFIED Hetzer, Roland UNSPECIFIED UNSPECIFIED UNSPECIFIED Huebler, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Ziemer, Gerhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Takkenberg, Johanna J. M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Hemmer, Wolfgang UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-496582
DOI:	10.1161/CIRCULATIONAHA.109.925800
Journal or Publication Title:	Circulation
Volume:	122
Number:	11
Page Range:	S. S216 - 8
Date:	2010
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Place of Publication:	PHILADELPHIA
ISSN:	1524-4539
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CRYOPRESERVED HOMOGRAFTS; ROOT REPLACEMENT; CHILDREN; OPERATION; PERFORMANCE Multiple languages Cardiac & Cardiovascular Systems; Peripheral Vascular Disease Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/49658