Universität zu Köln

Haendel, Alexander, Siebelmann, Sebastian, Hoz, Denis, Oegruenc, Ferdi, Matthaei, Mario, Cursiefen, Claus and Bachmann, Bjoern (2021). Comparison of Mini-DMEK versus predescemetal sutures as treatment of acute hydrops in keratoconus. Acta Ophthalmol., 99 (8). S. E1326 - 8. HOBOKEN: WILEY. ISSN 1755-3768

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Abstract

Purpose To compare two surgical treatment options for acute corneal hydrops in keratoconus: Mini-DMEK versus predescemetal sutures. Methods Sixteen patients were treated by either Mini-Descemet membrane endothelial keratoplasty (Mini-DMEK) (n = 7, group 1) or predescemetal sutures (n = 9, group 2) early after onset of acute hydrops. Visual acuity, maximum corneal thickness (SD-OCT) in the affected oedematous area, complications and recurrence rates were retrospectively compared between both groups. Measurements were taken immediately preoperatively as well as 1 day, 1 week and 1 month postoperatively (Table 1). Results Both groups showed reductions in corneal thickness and increased visual acuity shortly after surgery. In group 1 (average age 33 years +/- 7 years), the best corrected visual acuity (BCVA) increased from logMAR 1.65 +/- 0.7 before Mini-DMEK to logMAR 0.93 +/- 0.6 30 days after Mini-DMEK (p = 0.046). During that period, maximum corneal thickness decreased from 1159 +/- 338 mu m before surgery to 531 +/- 75 mu m after Mini-DMEK (p = 0.046). Patients from group 2 (average age 34 +/- 10 years) had a BCVA of logMAR 1.59 +/- 0.8 which increased to logMAR 0.97 +/- 0.5 (p = 0.014) 30 days after surgery. At the same time, the preoperative maximum corneal thickness decreased from 1439 +/- 272 mu m to 476 +/- 162 mu m (p = 0.014). There was no difference in corneal thickness or BCVA one month after the surgical intervention between both groups (p = 0.394 and p = 0.871). Conclusions Both techniques, Mini-DMEK and predescemetal sutures, are effective in the treatment of an acute hydrops in keratoconus. Mini-DMEK appears to be beneficial in large DM tears.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Haendel, Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED Siebelmann, Sebastian UNSPECIFIED UNSPECIFIED UNSPECIFIED Hoz, Denis UNSPECIFIED UNSPECIFIED UNSPECIFIED Oegruenc, Ferdi UNSPECIFIED UNSPECIFIED UNSPECIFIED Matthaei, Mario UNSPECIFIED UNSPECIFIED UNSPECIFIED Cursiefen, Claus UNSPECIFIED UNSPECIFIED UNSPECIFIED Bachmann, Bjoern UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-562462
DOI:	10.1111/aos.14835
Journal or Publication Title:	Acta Ophthalmol.
Volume:	99
Number:	8
Page Range:	S. E1326 - 8
Date:	2021
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1755-3768
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language Ophthalmology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/56246