Moshiri, Isabella, Karimi-Golkar, Damian, Schrittenlocher, Silvia, Cursiefen, Claus and Bachmann, Bjoern (2021). Outcomes of Pseudophakic, Phakic, and Triple DMEK. Cornea, 40 (10). S. 1253 - 1258. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1536-4798

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Abstract

Purpose: To evaluate the outcome of phakic and pseudophakic eyes treated by Descemet membrane endothelial keratoplasty (DMEK) versus DMEK combined with cataract surgery (triple DMEK). Methods: Retrospective cohort study based on the prospective Cologne DMEK data base. This study is a single-center analysis of 62 eyes undergoing phakic (age mean +/- SD 52 +/- 6.43), 518 eyes undergoing pseudophakic (73.5 +/- 8.57), and 557 eyes undergoing triple DMEK (67.93 +/- 8.57). Outcome measures were changes in best spectacle-corrected visual acuity (BSCVA), central corneal thickness, endothelial cell density (ECD), rebubbling rates within the first year after surgery, and the need for cataract surgery within the first 2 years after phakic DMEK. Results: The preoperative BSCVA (mean +/- SD; logarithm of the minimum angle of resolution) was 0.30 +/- 0.22 in the phakic, 0.63 +/- 0.45 in the pseudophakic, and 0.44 +/- 0.30 in the triple DMEK group (P < 0.001), which changed to 0.09 +/- 0.12, 0.14 +/- 0.1, and 0.1 +/- 0.1 (P < 0.001) 1 year after surgery, respectively. There was no difference in central corneal thickness (P = 0.929) and endothelial cell density (P = 0.606) 1 year postoperatively. Rebubbling rates in DMEK using SF6 20% for anterior chamber tamponade were not significantly different (P = 0.839). After phakic DMEK, 40% of eyes underwent cataract surgery within the second year. However, there was a high loss to follow-up in this group. Conclusions: Phakic and triple DMEK procedures tend to have a better 1-year BSCVA than pseudophakic DMEK, with no differences in all other parameters analyzed. However, patients from the pseudophakic DMEK group were older and already had worse BSCVA before surgery.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Moshiri, IsabellaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Karimi-Golkar, DamianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schrittenlocher, SilviaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cursiefen, ClausUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bachmann, BjoernUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-564145
DOI: 10.1097/ICO.0000000000002723
Journal or Publication Title: Cornea
Volume: 40
Number: 10
Page Range: S. 1253 - 1258
Date: 2021
Publisher: LIPPINCOTT WILLIAMS & WILKINS
Place of Publication: PHILADELPHIA
ISSN: 1536-4798
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
MEMBRANE ENDOTHELIAL KERATOPLASTY; POSTERIOR LAMELLAR KERATOPLASTY; CATARACT-SURGERY; EYES; PHACOEMULSIFICATION; EXTRACTION; 20-PERCENT; AIRMultiple languages
OphthalmologyMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/56414

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