Di Cristanziano, Veronica, Affeldt, Patrick, Trappe, Moritz, Wirtz, Maike, Heger, Eva, Knops, Elena, Kaiser, Rolf, Stippel, Dirk ORCID: 0000-0002-1107-0907, Mueller, Roman-Ulrich, Holtick, Udo, Scheid, Christoph, Kann, Martin ORCID: 0000-0003-2956-1699, Kurschat, Christine E. and Grundmann, Franziska ORCID: 0000-0002-5766-7477 (2021). Combined Therapy with Intravenous Immunoglobulins, Letermovir and (Val-)Ganciclovir in Complicated Courses of CMV-Infection in Transplant Recipients. Microorganisms, 9 (8). BASEL: MDPI. ISSN 2076-2607

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Abstract

The treatment options for cytomegalovirus (CMV) infections in immunosuppressed patients are limited, mainly consisting of (val-)ganciclovir (VGC/GCV) as the first-line treatment. We report on three transplant recipients, one stem cell transplant (allo-HSCT) patient and two kidney transplant (KTx) recipients, with prolonged CMV viremia treated with a combined therapy based on letermovir (LMV), CMV-specific intravenous immunoglobulins (IVIg), and VGC/GCV, which led to the sustained control of CMV viremia in all patients.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Di Cristanziano, VeronicaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Affeldt, PatrickUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Trappe, MoritzUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wirtz, MaikeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Heger, EvaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Knops, ElenaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kaiser, RolfUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stippel, DirkUNSPECIFIEDorcid.org/0000-0002-1107-0907UNSPECIFIED
Mueller, Roman-UlrichUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Holtick, UdoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Scheid, ChristophUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kann, MartinUNSPECIFIEDorcid.org/0000-0003-2956-1699UNSPECIFIED
Kurschat, Christine E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Grundmann, FranziskaUNSPECIFIEDorcid.org/0000-0002-5766-7477UNSPECIFIED
URN: urn:nbn:de:hbz:38-564394
DOI: 10.3390/microorganisms9081666
Journal or Publication Title: Microorganisms
Volume: 9
Number: 8
Date: 2021
Publisher: MDPI
Place of Publication: BASEL
ISSN: 2076-2607
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
CYTOMEGALOVIRUS; MANAGEMENTMultiple languages
MicrobiologyMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/56439

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