Frenzel, Lukas P. (2021). PI3K/BCL2: illusion or promise for RS? Blood, 137 (24). S. 3319 - 3323. WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020
Full text not available from this repository.Abstract
In this issue of Blood, Iannello et al report that phosphatidylinositol 3-kinase (PI3K) inhibitors can sensitize samples from patients with Richter syndrome (RS) to BCL2 inhibitors by regulating the expression of antiapoptotic molecules via glycogen synthase kinase 3 beta (GSK3 beta). The authors have thus provided a rationale for a novel drug combination to treat patients with chronic lymphocytic leukemia (CLL) and RS.(1)
| Item Type: | Journal Article | ||||||||
| Creators: |
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| URN: | urn:nbn:de:hbz:38-566538 | ||||||||
| DOI: | 10.1182/blood.2021011854 | ||||||||
| Journal or Publication Title: | Blood | ||||||||
| Volume: | 137 | ||||||||
| Number: | 24 | ||||||||
| Page Range: | S. 3319 - 3323 | ||||||||
| Date: | 2021 | ||||||||
| Publisher: | AMER SOC HEMATOLOGY | ||||||||
| Place of Publication: | WASHINGTON | ||||||||
| ISSN: | 1528-0020 | ||||||||
| Language: | English | ||||||||
| Faculty: | Unspecified | ||||||||
| Divisions: | Unspecified | ||||||||
| Subjects: | no entry | ||||||||
| Uncontrolled Keywords: |
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| URI: | http://kups.ub.uni-koeln.de/id/eprint/56653 |
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