Universität zu Köln

Kohle, Felix ORCID: 0000-0002-4429-0367, Kuwabara, Satoshi ORCID: 0000-0002-4716-8578 and Lehmann, Helmar Christoph (2021). Chronic inflammatory demyelinating polyneuropathy and pregnancy: systematic review. J. Neurol. Neurosurg. Psychiatry, 92 (5). S. 473 - 479. LONDON: BMJ PUBLISHING GROUP. ISSN 1468-330X

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Abstract

Pregnancy largely affects disease activity and clinical course in women with immune-mediated neurological disorders. Chronic inflammatory demyelinating polyneuropathy (CIDP) is rare but the most common chronic immune-mediated neuropathy; however, the effects of pregnancy on CIDP have never been investigated except case reports or series. We here provide a systematic review of the literature from 1 January 1969 to 30 June 2020 that revealed 24 women with CIDP, who had onset or relapse during pregnancy. Of these, 17 (71%) developed CIDP during the first pregnancy, and 8 (47%) had a relapse during subsequent pregnancies. Of the 17 patients, in whom the CIDP subtypes were determined, all of them had typical CIDP. First-line treatments for CIDP, such as corticosteroids, immunoglobulin and plasma exchange were efficacious and safe. We suggest that pregnancy can trigger typical CIDP in some women, and women with CIDP have a higher risk of relapse during pregnancy. The onset or relapse of CIDP during pregnancy is a rare but challenging constellation for physicians.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Kohle, Felix UNSPECIFIED orcid.org/0000-0002-4429-0367 UNSPECIFIED Kuwabara, Satoshi UNSPECIFIED orcid.org/0000-0002-4716-8578 UNSPECIFIED Lehmann, Helmar Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-571662
DOI:	10.1136/jnnp-2020-325321
Journal or Publication Title:	J. Neurol. Neurosurg. Psychiatry
Volume:	92
Number:	5
Page Range:	S. 473 - 479
Date:	2021
Publisher:	BMJ PUBLISHING GROUP
Place of Publication:	LONDON
ISSN:	1468-330X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language GUILLAIN-BARRE-SYNDROME; LUPUS-ERYTHEMATOSUS; PATIENT; POLYRADICULONEUROPATHY; POLYNEURITIS; PATHOGENESIS; ASSOCIATION; DELIVERY; CIDP Multiple languages Clinical Neurology; Psychiatry; Surgery Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/57166