Kochanek, Matthias, Borrega, Jorge Garcia, Beckmann, Laura, Neuhann, Julia, Gathof, Birgit S., Di Cristanziano, Veronica, Hagmann, Henning and Borrega, Garcia (2022). Plasma exchange with COVID-19 convalescent plasma in a patient with severe ANCA-associated vasculitis and COVID-19 pneumonia after rituximab therapy. Clin. Kidney J., 15 (1). S. 162 - 165. OXFORD: OXFORD UNIV PRESS. ISSN 2048-8513

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Abstract

The combination of coronavirus disease 2019 (COVID-19) pneumonia and pulmonary-renal syndrome due to ANCA-associated vasculitis (AAV) poses diagnostic uncertainty and a therapeutic dilemma. According to current limited knowledge of COVID-19, the application of commonly used drugs in AAV, cyclophosphamide (CYC) and rituximab (RTX), must be weighed carefully in active COVID-19 infection. We report a case of a 52-year-old male patient with concurrent severe COVID-19 pneumonia and acute relapse of pulmonary-renal syndrome due to AAV after recent RTX maintenance dose. The patient presented with severe hypoxaemia, complete B-cell depletion and severe acute respiratory syndrome coronavirus 2 viraemia. He was successfully treated with therapeutic plasma exchange employing COVID-19 convalescent plasma.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Kochanek, MatthiasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Borrega, Jorge GarciaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Beckmann, LauraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Neuhann, JuliaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gathof, Birgit S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Di Cristanziano, VeronicaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hagmann, HenningUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Borrega, GarciaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-573312
DOI: 10.1093/ckj/sfab095
Journal or Publication Title: Clin. Kidney J.
Volume: 15
Number: 1
Page Range: S. 162 - 165
Date: 2022
Publisher: OXFORD UNIV PRESS
Place of Publication: OXFORD
ISSN: 2048-8513
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
Urology & NephrologyMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/57331

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