Universität zu Köln

Kiessling, D., Rennings, C., Hild, M., Lappas, A., Dietlein, T. S., Roessler, G. F. and Widder, Randolf Alexander (2021). Impact of failed ab-interno trabeculectomy (trabectome) on subsequent XEN45 gel stent implantation in pseudophakic eyes. Int. Ophthalmol., 41 (12). S. 4047 - 4054. DORDRECHT: SPRINGER. ISSN 1573-2630

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Abstract

Purpose To determine the impact of failed ab-interno trabeculectomy on the postoperative outcome of subsequent XEN45 gel stent (Allergan, CA, USA) implantation in pseudophakic eyes. Methods In this retrospective single-center study, we included 60 pseudophakic eyes from 60 participants who underwent XEN45 gel stent implantation. Thirty eyes each underwent primary stent implantation (control group) or had previously undergone a failed ab-interno trabeculectomy (trabectome group). The groups were matched at a 1:1 ratio based on the following criteria: preoperative and maximum Intraocular pressure (IOP), preoperative medication score, cup/disk-ratio, follow-up time, best-corrected visual acuity at baseline, age, and the proportion of patients classified as primary open angle glaucoma or exfoliation glaucoma. We defined a successful surgery by the following three scores: an IOP reduction > 20% and IOP at the longest follow-up < 21 mmHg (Score A) or < 18 mmHg (Score B) or IOP <= 15 mmHg and an IOP reduction >= 40% (Score C). One open conjunctival revision was allowed in all scores, and a repeat surgery was considered a failure. Results Following an average follow-up period of 22 +/- 12 months, we observed a mean IOP reduction of 38%, from 23.5 +/- 5.2-14.5 +/- 5.0 mmHg. Comparative analyses between the groups did not reveal a significant difference in the postoperative IOP, postoperative medication score, side effects, revision rate, repeat surgery rate, or success rate. Conclusions Trabectome is a viable first-line procedure for medically uncontrolled glaucoma before filtering ab-interno microstent surgery is considered.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Kiessling, D. UNSPECIFIED UNSPECIFIED UNSPECIFIED Rennings, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Hild, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Lappas, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Dietlein, T. S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Roessler, G. F. UNSPECIFIED UNSPECIFIED UNSPECIFIED Widder, Randolf Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-575582
DOI:	10.1007/s10792-021-01977-w
Journal or Publication Title:	Int. Ophthalmol.
Volume:	41
Number:	12
Page Range:	S. 4047 - 4054
Date:	2021
Publisher:	SPRINGER
Place of Publication:	DORDRECHT
ISSN:	1573-2630
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PSEUDOEXFOLIATION GLAUCOMA; TRIPLE PROCEDURE; SUCCESS RATES; RISK-FACTORS; SURGERY; TRABECULOTOMY; CATARACT; FAILURE; SAFETY Multiple languages Ophthalmology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/57558