Vollstadt-Klein, Sabine ORCID: 0000-0002-6210-672X, Grundinger, Nadja, Gorig, Tatiana, Szafran, Daria, Althaus, Astrid, Mons, Ute and Schneider, Sven (2021). Study protocol: evaluation of the addictive potential of e-cigarettes (EVAPE): neurobiological, sociological, and epidemiological perspectives. BMC Psychol., 9 (1). LONDON: SPRINGERNATURE. ISSN 2050-7283

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Abstract

Background: Tobacco use is the largest preventable cause of diseases and deaths; reducing tobacco intake is, therefore, an urgent public health goal. In recent years, e-cigarettes have been marketed as a 'healthier' alternative to tobacco smoking, whilst product features have evolved tremendously in the meantime. A lively scientific debate has developed regarding the potential benefits and risks of e-cigarettes although, surprisingly, there are few studies investigating the addictive potential of nicotine-containing e-cigarettes. The present work comprises three work packages investigating the addictive potential of e-cigarettes from different perspectives: (1) the neurobiological addictive potential of e-cigarettes; (2) the experience and perception of dependence symptoms among users of e-cigarettes in a social context; and (3) the epidemiological perspective regarding factors influencing the potential for dependence. Methods: Work package I: the neurobiological study will investigate the key elements of addiction in e-cigarettes compared to tobacco cigarettes using neurobiological and neuropsychological correlates associated with craving, incentive motivation, cue reactivity and attentional bias. Work package II: the sociological study part examines selfreports on the experience and perception of dependence symptoms in a social context, using focus group interviews and the analysis of posts in online discussion forums on e-cigarettes. Work package III: the epidemiological study part focuses on tolerance development and the role of psychosocial and product factors by analyzing longitudinal data from the International Tobacco Control Policy Evaluation Project (ITC). Discussion: The present study offers a chosen mix of three methodological approaches, thereby comprehensively examining core symptoms of positive and negative reinforcement in addiction. Whether e-cigarettes are as reinforcing and addictive as combustible tobacco cigarettes is an important public health issue with implications for prevention and treatment programs.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Vollstadt-Klein, SabineUNSPECIFIEDorcid.org/0000-0002-6210-672XUNSPECIFIED
Grundinger, NadjaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gorig, TatianaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Szafran, DariaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Althaus, AstridUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mons, UteUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schneider, SvenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-575864
DOI: 10.1186/s40359-021-00682-8
Journal or Publication Title: BMC Psychol.
Volume: 9
Number: 1
Date: 2021
Publisher: SPRINGERNATURE
Place of Publication: LONDON
ISSN: 2050-7283
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
INCENTIVE-SENSITIZATION THEORY; EXCLUSIVE E-CIGARETTE; ELECTRONIC CIGARETTES; NICOTINE DEPENDENCE; ATTENTIONAL BIAS; MONOAMINE-OXIDASE; CUE-REACTIVITY; SMOKING CUES; INDIVIDUAL-DIFFERENCES; ABUSE LIABILITYMultiple languages
Psychology, MultidisciplinaryMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/57586

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