Universität zu Köln

Andreou, Maria ORCID: 0000-0002-7867-3163 and Peristeri, Eleni (2021). Interference Resolution in Nonfluent Variant Primary Progressive Aphasia: Evidence From a Picture-Word Interference Task. Cogn. Behav. Neurol., 34 (1). S. 11 - 26. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1543-3641

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Abstract

Background: Picture-word interference tasks have been used to investigate (a) the time course of lexical access in individuals with primary progressive aphasia (PPA) and (b) how these individuals resolve competition during lexical selection. Objective: To investigate the time course of Greek-speaking individuals with PPA to produce grammatical gender-marked determiner phrases by examining their picture-naming latencies in the context of distractor words. Method: Eight individuals with nonfluent variant PPA (nfv-PPA; M age = 62.8 years) and eight cognitively intact controls (M age = 61.1 years) participated in our study. In a picture-word interference task, the study participants named depicted objects by producing determiner + noun sequences. Interference was generated by manipulating the grammatical gender of the depicted objects and distractor words. Two stimulus onset asynchronies were used: +200 ms and +400 ms. Results: The individuals with nfv-PPA exhibited longer picture-naming latencies than the controls (P = 0.003). The controls exhibited interference from incongruent distractors at both asynchronies (P < 0.001); the individuals with PPA exhibited interference from incongruent distractors only at the +400-ms interval (P = 0.002). The gender-congruency effect was stronger for the individuals with PPA than for the controls at the +400-ms interval (P = 0.05); the opposite pattern was observed at the +200-ms interval (P = 0.024). Conclusion: Gender interference resolution was abnormal in the individuals with nfv-PPA. The results point to deficits in lexicosyntactic networks that compromised the time course of picture-naming production.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Andreou, Maria UNSPECIFIED orcid.org/0000-0002-7867-3163 UNSPECIFIED Peristeri, Eleni UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-577108
DOI:	10.1097/WNN.0000000000000255
Journal or Publication Title:	Cogn. Behav. Neurol.
Volume:	34
Number:	1
Page Range:	S. 11 - 26
Date:	2021
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Place of Publication:	PHILADELPHIA
ISSN:	1543-3641
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language NOUN PHRASE PRODUCTION; GRAMMATICAL GENDER; SEMANTIC INTERFERENCE; PREFRONTAL CORTEX; LEXICAL ACCESS; RETRIEVAL; RECOGNITION; IMPAIRMENTS; AGREEMENT; MODALITY Multiple languages Behavioral Sciences; Clinical Neurology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/57710