Universität zu Köln

Useini, Dritan ORCID: 0000-0002-8312-330X, Beluli, Blerta ORCID: 0000-0003-2155-0354, Christ, Hildegard, Schloemicher, Markus, Ewais, Elias, Haldenwang, Peter, Patsalis, Polykarpos, Moustafine, Vadim, Bechtel, Matthias and Strauch, Justus (2021). Transcatheter aortic valve replacement using the SAPIEN 3 valve versus surgical aortic valve replacement using the rapid deployment INTUITY valve: Midterm outcomes. J. Card. Surg., 36 (2). S. 610 - 618. HOBOKEN: WILEY. ISSN 1540-8191

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Abstract

Objectives Little data have been published on the midterm effect of transapical/transfemoral-transcatheter aortic valve replacement (TA-/TF-TAVR) using the Edwards SAPIEN 3 valve (S3). We aimed to compare the outcomes after TA-/TF-TAVR utilizing the S3 (TA-/TF-S3) valve with those after surgical aortic valve replacement utilizing the rapid deployment Edwards INTUITY valve (RD-SAVR). Methods Between March 2012 and April 2018, 122 patients with aortic stenosis underwent TA-S3, 77 patients underwent TF-S3 and 182 patients underwent RD-SAVR through partial sternotomy at our institution. We conducted clinical and echocardiographic midterm follow-ups. The primary outcomes of the study were the incidence of new pacemakers permanent pacemaker implantation (PPI), the occurrence of paravalvular leakage (PVL) and the hemodynamic performance of the valves. Results All study groups were at intermediate surgical risk. The 30-day all-cause mortality and stroke rates in the TA-S3, TF-S3, and RD-SAVR groups were 4.1% and 1.6%, 3.9% and 2.6%, and 3.8% and 2.2%, respectively. The RD-SAVR group had significantly smaller PVL and PPI rates than did the TA-/TF-S3 group (p < .0001). At the discharge, the one-year postprocedure mean gradients were 9 +/- 5.1/10 +/- 4.5 mmHg, 11 +/- 4.1/12 +/- 3.8 mmHg, and 10.1 +/- 4.3/10.4 +/- 2.6 mmHg in the TA-S3, TF-S3, and RD-SAVR groups, respectively. Midterm valve thrombosis, Re-TAVR/SVAR were low and similar among the study groups, whereas endocarditis was higher in the TAVR group. Conclusion RD-SAVR was superior to TA-/TF-S3 in the PVL and PPI rates. We observed similar early outcomes and valve hemodynamics. The endocarditis was higher in the TAVR group.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Useini, Dritan UNSPECIFIED orcid.org/0000-0002-8312-330X UNSPECIFIED Beluli, Blerta UNSPECIFIED orcid.org/0000-0003-2155-0354 UNSPECIFIED Christ, Hildegard UNSPECIFIED UNSPECIFIED UNSPECIFIED Schloemicher, Markus UNSPECIFIED UNSPECIFIED UNSPECIFIED Ewais, Elias UNSPECIFIED UNSPECIFIED UNSPECIFIED Haldenwang, Peter UNSPECIFIED UNSPECIFIED UNSPECIFIED Patsalis, Polykarpos UNSPECIFIED UNSPECIFIED UNSPECIFIED Moustafine, Vadim UNSPECIFIED UNSPECIFIED UNSPECIFIED Bechtel, Matthias UNSPECIFIED UNSPECIFIED UNSPECIFIED Strauch, Justus UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-578414
DOI:	10.1111/jocs.15275
Journal or Publication Title:	J. Card. Surg.
Volume:	36
Number:	2
Page Range:	S. 610 - 618
Date:	2021
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1540-8191
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language EDWARDS SAPIEN; PARAVALVULAR REGURGITATION; CLINICAL-OUTCOMES; 1-YEAR OUTCOMES; IMPLANTATION; PREDICTORS; GENERATION; IMPACT; METAANALYSIS; ASSOCIATION Multiple languages Cardiac & Cardiovascular Systems; Surgery Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/57841