Universität zu Köln

Useini, Dritan ORCID: 0000-0002-8312-330X, Beluli, Blerta ORCID: 0000-0003-2155-0354, Christ, Hildegard ORCID: 0000-0003-3235-2994, Muegge, Andreas, Patsalis, Polykarpos, Schloemicher, Markus, Haldenwang, Peter, Bechtel, Matthias and Strauch, Justus (2021). Oversized versus Non-oversized Prosthesis: Midterm Outcomes after Transcatheter Aortic Valve Replacement Using SAPIEN 3 Valve. Thorac. Cardiovasc. Surg., 69 (5). S. 445 - 455. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1439-1902

Full text not available from this repository.

Abstract

Background A certain degree of prosthesis oversizing is recommended for the SAPIEN 3 (S3; Edwards Lifesciences Corp., Irvine, California, United States) to ensure device success. We aimed to investigate midterm outcomes in patients who received oversized (OS) S3 valve after transapical-transcatheter aortic valve replacement (TA-TAVR). Methods Out of 122 patients with aortic stenosis who underwent TA-TAVR using S3 at our institution, 42 received OS prosthesis. We used computed tomography (CT) derived effective diameter to assess oversizing. We defined oversizing if the labeled diameter of the selected valve for implantation was >= 2mm bigger than the effective annulus diameter calculated by the annulus area. We conducted a midterm follow-up and compared the OS cohort with the non-OS (nOS) cohort. Results The study groups showed similar risk score and age (STS [Society of Thoracic Surgery] score: 5.43; mean age: 80.7 +/- 5.7). The 30-day mortality was 7.1% in OS versus 2.4% in nOS. The 30-day all-stroke was 2.4% in OS versus 0% in nOS. The 1- and 3-year all-cause mortality were 28.5 and 42.8% in OS versus 21.9 and 26.8% in nOS, respectively. Midterm freedom from death and from cardiocerebral events was similar in both groups. Moderate/severe paravalvular leakage occurred in 0% in OS versus 5.4% in nOS. The postdilation rate was 7.1% in OS versus 15.3% in nOS. The rate of new permanent pacemaker implantation (PPI) was 15.7% in OS versus 9.3% in nOS. The STS score was detected as an independent predictor of mortality. Conclusion Oversizing reduces the risk of device failure and intraprocedural postdilation but increases the risk of PPI. Early and midterm morbidity and mortality after OS and nOS with S3 are comparable.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Useini, Dritan UNSPECIFIED orcid.org/0000-0002-8312-330X UNSPECIFIED Beluli, Blerta UNSPECIFIED orcid.org/0000-0003-2155-0354 UNSPECIFIED Christ, Hildegard UNSPECIFIED orcid.org/0000-0003-3235-2994 UNSPECIFIED Muegge, Andreas UNSPECIFIED UNSPECIFIED UNSPECIFIED Patsalis, Polykarpos UNSPECIFIED UNSPECIFIED UNSPECIFIED Schloemicher, Markus UNSPECIFIED UNSPECIFIED UNSPECIFIED Haldenwang, Peter UNSPECIFIED UNSPECIFIED UNSPECIFIED Bechtel, Matthias UNSPECIFIED UNSPECIFIED UNSPECIFIED Strauch, Justus UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-579554
DOI:	10.1055/s-0040-1713168
Journal or Publication Title:	Thorac. Cardiovasc. Surg.
Volume:	69
Number:	5
Page Range:	S. 445 - 455
Date:	2021
Publisher:	GEORG THIEME VERLAG KG
Place of Publication:	STUTTGART
ISSN:	1439-1902
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PARAVALVULAR REGURGITATION; IMPACT; IMPLANTATION; PREDICTORS; ASSOCIATION Multiple languages Cardiac & Cardiovascular Systems; Respiratory System; Surgery Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/57955