Universität zu Köln

Ladage, Dennis, Rosgen, Delia, Schreiner, Clemens, Ladage, Dorothee, Adler, Christoph, Harzer, Oliver and Braun, Ralf J. (2021). Persisting Antibody Response to SARS-CoV-2 in a Local Austrian Population. Front. Med., 8. LAUSANNE: FRONTIERS MEDIA SA. ISSN 2296-858X

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Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic recently. The prevalence and persistence of antibodies following a peak SARS-CoV-2 infection provides insights into the potential for some level of population immunity. In June 2020, we succeeded in testing almost half of the population of an Austrian town with a higher incidence of COVID-19 infection. We performed a follow-up study to reassess the prevalence of SARS-CoV-2-specific IgA and IgG antibodies with 68 participants of the previous study. We found that the prevalence of IgG or IgA antibodies remained remarkably stable, with 84% of our cohort prevailing SARS-CoV-2-specific antibodies (only a slight decrease from 93% 4 months before). In most patients with confirmed COVID-19 seroconversion potentially provides immunity to reinfection. Our results suggest a stable antibody response observed for at least 6 months post-infection with implications for developing strategies for testing and protecting the population.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Ladage, Dennis UNSPECIFIED UNSPECIFIED UNSPECIFIED Rosgen, Delia UNSPECIFIED UNSPECIFIED UNSPECIFIED Schreiner, Clemens UNSPECIFIED UNSPECIFIED UNSPECIFIED Ladage, Dorothee UNSPECIFIED UNSPECIFIED UNSPECIFIED Adler, Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED Harzer, Oliver UNSPECIFIED UNSPECIFIED UNSPECIFIED Braun, Ralf J. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-579775
DOI:	10.3389/fmed.2021.653630
Journal or Publication Title:	Front. Med.
Volume:	8
Date:	2021
Publisher:	FRONTIERS MEDIA SA
Place of Publication:	LAUSANNE
ISSN:	2296-858X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language Medicine, General & Internal Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/57977