Universität zu Köln

Echterdiek, Fabian ORCID: 0000-0001-7239-4959, Kitterer, Daniel, Dippon, Jurgen, Paul, Gregor ORCID: 0000-0002-1075-4362, Schwenger, Vedat and Latus, Joerg (2021). Impact of cardiopulmonary resuscitation on outcome of kidney transplantations from braindead donors aged >= 65 years. Clin. Transplant., 35 (11). HOBOKEN: WILEY. ISSN 1399-0012

Full text not available from this repository.

Abstract

Introduction Patients with a history of cardiopulmonary resuscitation (CPR) and subsequent brain death are frequently evaluated for organ donation. Whether kidneys from >= 65-year-old braindead donors with a history of CPR can be transplanted with satisfactory outcomes is unknown. Material & Methods All kidney transplants (KTs) from >= 65-year-old donors performed at our center from 1999 to 2018 (n = 185) were retrospectively analyzed and outcome was compared for KTs from donors with and without a history of CPR (n = 27 and n = 158, respectively). Results No significant differences in the incidence of delayed graft function (DGF) as well as 1- and 3-year graft function were observed between the CPR and the no-CPR group (DGF: 26.0% vs. 31.0%, p = .76; 1-year serum creatinine: 150.4 mu mol/L vs. 177.0 mu mol/L, p = .11; 3-year serum creatinine: 150.4 mu mol/L vs. 168.2 mu mol/L, p = .52, respectively). Death-censored graft survival was comparable after 1 and 5 years (CPR group: 81.5% and 76.7% vs. no-CPR group: 86.6% and 75.7%, p = .70). Likewise, patient survival was not significantly different. Multivariable Cox regression analysis also did not identify CPR as a significant risk factor for graft loss or death. Conclusion Our study suggests that, following stringent donor selection, the outcome of KTs from >= 65-year-old braindead donors with and without a history of CPR is comparable.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Echterdiek, Fabian UNSPECIFIED orcid.org/0000-0001-7239-4959 UNSPECIFIED Kitterer, Daniel UNSPECIFIED UNSPECIFIED UNSPECIFIED Dippon, Jurgen UNSPECIFIED UNSPECIFIED UNSPECIFIED Paul, Gregor UNSPECIFIED orcid.org/0000-0002-1075-4362 UNSPECIFIED Schwenger, Vedat UNSPECIFIED UNSPECIFIED UNSPECIFIED Latus, Joerg UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-581200
DOI:	10.1111/ctr.14452
Journal or Publication Title:	Clin. Transplant.
Volume:	35
Number:	11
Date:	2021
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1399-0012
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language EUROTRANSPLANT SENIOR PROGRAM; RENAL-TRANSPLANTATION; CARDIAC-ARREST; DECEASED DONORS; RISK-FACTORS; HEART; INJURY; RECIPIENTS; OLDER Multiple languages Surgery; Transplantation Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/58120