Wagner, Britta Janina, Hobbach, Hans-Peter, Hobbach, Anastasia Janina, Hieggelke, Lena Katharina, Grond, Martin, Monsefi, Nadejda and Buettner, Reinhard . Cardiac metastasis causes paradoxical malignant embolism. Cancer Rep.-US. HOBOKEN: WILEY. ISSN 2573-8348

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Abstract

Background Embolic events play an important role in clinical everyday practice. Malignant arterial embolism is a rare nevertheless often fatal entity for cardiac, cerebral or systemic ischemia, requiring immediate diagnosis and treatment. Case This is a case report of a 65 years-old female, suffering from pulmonal adenocarcinoma, who was hospitalized due to neurological deficits caused by an acute ischemic stroke, followed by anterior myocardial infarction within 3 days. Diagnostic work-up revealed metastasis of the pulmonal adenocarcinoma in the right atrium and a patent foramen ovale. Histopathological examination of the coronary embolus verified paradoxical arterial embolism of the pulmonal adenocarcinoma into a coronary vessel and consequently cerebral arteries. Conclusion The present case underlines the need for (i), consideration of malignant embolism, (ii) histopathological examination of the embolus to determine its etiology, and (iii) interdisciplinary discussion of individual therapeutic and prevention strategies in cancer patients with cerebral, cardiac or systemic embolic events.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Wagner, Britta JaninaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hobbach, Hans-PeterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hobbach, Anastasia JaninaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hieggelke, Lena KatharinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Grond, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Monsefi, NadejdaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Buettner, ReinhardUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-581808
DOI: 10.1002/cnr2.1513
Journal or Publication Title: Cancer Rep.-US
Publisher: WILEY
Place of Publication: HOBOKEN
ISSN: 2573-8348
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
PATENT FORAMEN OVALE; CANCER; PLATELETS; THROMBOSIS; CLOSURE; AGENTSMultiple languages
OncologyMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/58180

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