Wierzbicka, Malgorzata, Klussmann, Jens Peter ORCID: 0000-0002-8223-7954, San Giorgi, Michel R., Wuerdemann, Nora and Dikkers, Frederik G. (2021). Oral and laryngeal HPV infection: Incidence, prevalence and risk factors, with special regard to concurrent infection in head, neck and genitals. Vaccine, 39 (17). S. 2344 - 2351. OXFORD: ELSEVIER SCI LTD. ISSN 1873-2518

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Abstract

This review focuses on the importance of oral and laryngeal HPV infection which is present in majority of sexually active individuals at least once in their lifetime. Despite testing, still little is known about prevalence rates, determinants and, especially, the concurrent HPV infection in head and neck, and genitals. The purpose of this review is to clarify some issues of oral HPV incidence, prevalence, and to demonstrate the difficulties in identification of asymptomatic oral HPV carriers. The main premise to take up this topic is the high and still increasing risk for development of oropharyngeal cancer, and potential benefit from screening strategies, education programs and HPV vaccination. Transmission of HPV to the oral cavity and oropharynx is hypothesized to occur mainly through sexual contact. The exposure of oropharyngeal mucosa to HPV infection with consequence of increased risk for oropharyngeal carcinoma depends on specific sexual behavior. Male gender, older age, race or ethnicity, oral hygiene and current cigarette smoking are independently associated with any prevalent oral HPV infection. (C) 2021 The Author(s). Published by Elsevier Ltd.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Wierzbicka, MalgorzataUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Klussmann, Jens PeterUNSPECIFIEDorcid.org/0000-0002-8223-7954UNSPECIFIED
San Giorgi, Michel R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wuerdemann, NoraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dikkers, Frederik G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-581882
DOI: 10.1016/j.vaccine.2021.03.047
Journal or Publication Title: Vaccine
Volume: 39
Number: 17
Page Range: S. 2344 - 2351
Date: 2021
Publisher: ELSEVIER SCI LTD
Place of Publication: OXFORD
ISSN: 1873-2518
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
HUMAN-PAPILLOMAVIRUS INFECTION; OROPHARYNGEAL CANCER; NATURAL-HISTORY; SEXUAL-BEHAVIORS; UNITED-STATES; CHLAMYDIA-TRACHOMATIS; PERIODONTAL-DISEASE; CERVICAL-CANCER; MEN; WOMENMultiple languages
Immunology; Medicine, Research & ExperimentalMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/58188

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