Universität zu Köln

Larsen, Petra P., Mueller, Andreas, Lagreze, Wolf A., Holz, Frank G., Stahl, Andreas and Krohne, Tim U. (2021). Incidence of retinopathy of prematurity in Germany: evaluation of current screening criteria. Arch. Dis. Child.-Fetal Neonatal Ed., 106 (2). S. F189 - 5. LONDON: BMJ PUBLISHING GROUP. ISSN 1468-2052

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Abstract

Objective To evaluate current screening criteria for retinopathy of prematurity (ROP) by investigating the incidence of ROP requiring treatment in infants with gestational age (GA) >= 30 weeks or postmenstrual age (PMA) <32 weeks in Germany. Methods Three patient databases were analysed, that is, the German Quality Assurance Procedure in Neonatology (years 2011-2017; n=52 461 infants screened for ROP, 1505 infants treated for ROP), the German Retina.net ROP Registry (years 2011-2018; n=281 treated infants) and the ROP screening programme of two German university hospitals (years 2012-2016; n=837 screened infants). Results In the analysed cohorts, infants with GA >= 30 weeks represented 33.1%-38.5% of the screening populations but only 1.40%-1.42% of the cases requiring ROP treatment. In a cohort of 281 infants treated for ROP, all 4 infants with GA >= 30 weeks had additional risk factors for ROP including prolonged oxygen supplementation and/or significant comorbidities. Five infants (1.8%) were treated at 32 weeks PMA and none at PMA <32 weeks. Conclusions In the investigated cohorts, preterm infants with GA >= 30 weeks carried a very low or no risk for developing treatment-requiring ROP unless additional risk factors were present, and no treatment was performed earlier than 32 weeks PMA. These findings are of relevance for the ongoing re-evaluation of ROP screening criteria.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Larsen, Petra P. UNSPECIFIED UNSPECIFIED UNSPECIFIED Mueller, Andreas UNSPECIFIED UNSPECIFIED UNSPECIFIED Lagreze, Wolf A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Holz, Frank G. UNSPECIFIED UNSPECIFIED UNSPECIFIED Stahl, Andreas UNSPECIFIED UNSPECIFIED UNSPECIFIED Krohne, Tim U. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-584872
DOI:	10.1136/archdischild-2020-319767
Journal or Publication Title:	Arch. Dis. Child.-Fetal Neonatal Ed.
Volume:	106
Number:	2
Page Range:	S. F189 - 5
Date:	2021
Publisher:	BMJ PUBLISHING GROUP
Place of Publication:	LONDON
ISSN:	1468-2052
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language Pediatrics Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/58487