Universität zu Köln

Krajewski, Piotr K., Matusiak, Lukasz ORCID: 0000-0003-2067-4929, von Stebut, Esther ORCID: 0000-0001-9802-9642, Schultheis, Michael, Kirschner, Uwe, Nikolakis, Georgios and Szepietowski, Jacek C. (2021). Quality-of-Life Impairment among Patients with Hidradenitis Suppurativa: A Cross-Sectional Study of 1795 Patients. Life-Basel, 11 (1). BASEL: MDPI. ISSN 2075-1729

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Abstract

The chronic, inflammatory skin disorder hidradenitis suppurativa (HS) is associated well documented negative influences on patients' quality of life (QoL). The aim of this study was to present more robust data on patients' QoL impairment by demographic data and its correlation with well-known HS risk factors on a cohort of 1795 German patients. The instrument used for measuring QoL in this study was the Dermatology Life Quality Index (DLQI). Overall, patients reported a very large effect of HS on their QoL (mean DLQI: 13.2 +/- 8.1 points), and 22% of the analyzed population even reported to consider the effect as extremely large. Women tended to experience significantly higher impairment than men (p < 0.001). QoL impairment correlated positively with pain (r = 0.581, p < 0.001), HS severity (measured by the International Hidradenitis Suppurativa Severity Score System (IHS4)) as well as Hurley. Neck involvement tended to decrease QoL significantly more than any other location (14.7 +/- 8.3 points). This study confirms the enormous influence of HS on patients' QoL in a large cohort. Knowledge of QoL impairment in such patients is crucial for proper understanding and holistic management of this disease.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Krajewski, Piotr K. UNSPECIFIED UNSPECIFIED UNSPECIFIED Matusiak, Lukasz UNSPECIFIED orcid.org/0000-0003-2067-4929 UNSPECIFIED von Stebut, Esther UNSPECIFIED orcid.org/0000-0001-9802-9642 UNSPECIFIED Schultheis, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Kirschner, Uwe UNSPECIFIED UNSPECIFIED UNSPECIFIED Nikolakis, Georgios UNSPECIFIED UNSPECIFIED UNSPECIFIED Szepietowski, Jacek C. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-587347
DOI:	10.3390/life11010034
Journal or Publication Title:	Life-Basel
Volume:	11
Number:	1
Date:	2021
Publisher:	MDPI
Place of Publication:	BASEL
ISSN:	2075-1729
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language Biology; Microbiology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/58734