Zietze, Henny Anna, Cabral, Carlos, Theobald, Karlheinz, Ihle, Peter, Pittrow, David, Kienitz, Carsten and Augustin, Matthias (2021). Epidemiology and treatment of adult patients with atopic dermatitis Analysis of longitudinal data of the statutory health insurance scheme. Hautarzt, 72 (11). S. 963 - 975. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-1173

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Abstract

Background The goal was to report incidence, prevalence, and treatment patterns in adult atopic dermatitis (AD) patients in the German statutory health insurance system. Patient and methods Anonymized claims data were evaluated at patient level for 3.3 million persons insured by six different statutory health insurance companies (SHI). Patients for whom the ICD-10 diagnosis code L20 (AD) was applied at least twice were analyzed and data on prescription patterns for AD were reported for the years 2011-2015. Results AD prevalence in adults was 1.6-1.9% in 2012-2015. Annual incidence was 0.28%. In Q3/Q4 2015, 44.2% of the adult population with AD diagnosis by a dermatologist received prescriptions for AD medications: 1.6% low-potency topical glucocorticoids (without previous prescription of systemic drugs), 46.9% moderate or high-potency topical glucocorticoids or topical calcineurin inhibitors, 23.9% current systemic therapy (systemic glucocorticoids, ciclosporin, methotrexate, azathioprine, mycophenolate mofetil) and 27.6% systemic therapy in the past. Conclusions The AD prevalence estimate was in the range of previous reports (1.35-4%) that used different methodologies. Based on treatment proxy, it appeared that almost more than half of AD patients treated with prescription ready-to-use drugs had a severe form of AD which required treatment with systemic drugs.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Zietze, Henny AnnaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cabral, CarlosUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Theobald, KarlheinzUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ihle, PeterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pittrow, DavidUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kienitz, CarstenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Augustin, MatthiasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-590029
DOI: 10.1007/s00105-021-04859-5
Journal or Publication Title: Hautarzt
Volume: 72
Number: 11
Page Range: S. 963 - 975
Date: 2021
Publisher: SPRINGER HEIDELBERG
Place of Publication: HEIDELBERG
ISSN: 1432-1173
Language: German
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
SECONDARY DATA-ANALYSIS; EUROPEAN GUIDELINES; ALLERGIC DISEASES; PREVALENCE; CHILDREN; MANAGEMENT; INTERVIEW; BURDEN; COHORTMultiple languages
DermatologyMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/59002

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