Anneveldt, K. J., Verpalen, I. M., Nijholt, I. M., Dijkstra, J. R., van den Hoed, R. D., Van't Veer-ten Kate, M., de Boer, E., van Osch, J. A. C., Heijman, E., Naber, H. R., Ista, E., Franx, A., Veersema, S., Huirne, J. A. F., Schutte, J. M. and Boomsma, M. F. (2021). Lessons learned during implementation of MR-guided High-Intensity Focused Ultrasound treatment of uterine fibroids. Insights Imaging, 12 (1). NEW YORK: SPRINGER. ISSN 1869-4101

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Abstract

Background: Although promising results have been reported for Magnetic Resonance image-guided High-Intensity Focused Ultrasound (MR-HIFU) treatment of uterine fibroids, this treatment is not yet widely implemented in clinical practice. During the implementation of a new technology, lessons are learned and an institutional learning-curve often has to be completed. The primary aim of our prospective cohort study was to characterize our learning-curve based on our clinical outcomes. Secondary aims included identifying our lessons learned during implementation of MR-HIFU on a technical, patient selection, patient counseling, medical specialists and organizational level. Results: Our first seventy patients showed significant symptom reduction and improvement of quality of life at 3, 6 and 12 months after MR-HIFU treatment compared to baseline. After the first 25 cases, a clear plateau phase was reached in terms of failed treatments. The median non-perfused volume percentage of these first 25 treatments was 44.6% (range: 0-99.7), compared to a median of 74.7% (range: 0-120.6) for the subsequent treatments. Conclusions: Our findings describe the learning-curve during the implementation of MR-HIFU and include straight-forward suggestions to shorten learning-curves for future users. Moreover, the lessons we learned on technique, patient selection, patient counseling, medical specialists and organization, together with the provided supplements, may be of benefit to other institutions aiming to implement MR-HIFU treatment of uterine fibroids.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Anneveldt, K. J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Verpalen, I. M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Nijholt, I. M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dijkstra, J. R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
van den Hoed, R. D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Van't Veer-ten Kate, M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
de Boer, E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
van Osch, J. A. C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Heijman, E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Naber, H. R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ista, E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Franx, A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Veersema, S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Huirne, J. A. F.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schutte, J. M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Boomsma, M. F.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-593696
DOI: 10.1186/s13244-021-01128-w
Journal or Publication Title: Insights Imaging
Volume: 12
Number: 1
Date: 2021
Publisher: SPRINGER
Place of Publication: NEW YORK
ISSN: 1869-4101
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
ARTERY EMBOLIZATION; IMPROVEMENT; OUTCOMESMultiple languages
Radiology, Nuclear Medicine & Medical ImagingMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/59369

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