Salunkhe, G., Weissbrodt, K., Feige, B., Saville, C. W. N., Berger, A., Dundon, N. M., Bender, S., Smyrnis, N., Beauducel, A., Biscaldi, M. and Klein, C. (2021). Examining the Overlap Between ADHD and Autism Spectrum Disorder (ASD) Using Candidate Endophenotypes of ADHD. J. Atten. Disord., 25 (2). S. 217 - 233. THOUSAND OAKS: SAGE PUBLICATIONS INC. ISSN 1557-1246

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Abstract

Objective: Recent discussions of aetiological overlap between ADHD and Autism Spectrum Disorder (ASD) require comparative studying of these disorders. Method: We examined performance of ASD patients with (ASD+) and without (ASD-) comorbid ADHD, ADHD patients, and controls for selected putative endophenotypes of ADHD: Intrasubject Variability (ISV) of reaction times, working memory (WM), inhibition, and temporal processing. Results: We found that patients with ADHD or ASD+, but not ASD-, had elevated ISV across the entire task battery and temporal processing deficits, and that none of the groups were impaired in WM or inhibition. High levels of ISV and generally poor performance in ASD+ patients were only partially due to additive effects of the pure disorders. Conclusion: Overall, we conclude that, within our limited but heterogeneous task battery, ISV and temporal processing deficits are most sensitive to ADHD symptomatology and that controlling for ADHD comorbidity is mandatory when assessing ISV in autism.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Salunkhe, G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Weissbrodt, K.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Feige, B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Saville, C. W. N.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Berger, A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dundon, N. M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bender, S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Smyrnis, N.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Beauducel, A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Biscaldi, M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Klein, C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-593795
DOI: 10.1177/1087054718778114
Journal or Publication Title: J. Atten. Disord.
Volume: 25
Number: 2
Page Range: S. 217 - 233
Date: 2021
Publisher: SAGE PUBLICATIONS INC
Place of Publication: THOUSAND OAKS
ISSN: 1557-1246
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
Psychology, Developmental; PsychiatryMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/59379

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