Universität zu Köln

Peristeri, Eleni, Messinis, Lambros, Kosmidis, Mary H., Nasios, Grigorios, Mentis, Alexios-Fotios A., Siokas, Vasileios, Aloizou, Athina-Maria, Kotrotsios, Anastasios, Andreou, Maria ORCID: 0000-0002-7867-3163 and Dardiotis, Efthimios (2021). The Impact of Primary Progressive Aphasia on Picture Naming and General Language Ability. Cogn. Behav. Neurol., 34 (3). S. 188 - 200. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1543-3641

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Abstract

Background: Primary progressive aphasia (PPA) is a clinical syndrome that is characterized by progressive deterioration of language while other cognitive domains remain relatively intact. The extent to which print exposure and cortical volume atrophy jointly influence picture naming and general language ability in individuals with PPA remains underexplored. Objective: To investigate the language performance of individuals with the nonfluent variant of primary progressive aphasia (nfvPPA) and to explore the impact of print exposure and cortical volume atrophy on their language ability. Method: We compared 14 Greek individuals with nfvPPA and similar age, education, disease duration, and cognitive ability with age-, gender- and education-matched Greek controls on picture naming and on language tasks of the Boston Diagnostic Aphasia Examination-Short Form, including oral word reading, word and sentence repetition, complex ideational material, and reading comprehension. The effects of print exposure and left-hemisphere cortical volume on the individuals' language performance were estimated through stepwise regression models. Results: The language performance of the individuals with nfvPPA was affected by print exposure and cortical volume atrophy. Picture naming and word reading were affected by print exposure. The highest contributions of cortical volume atrophy were found for the repetition, complex ideational material, and reading comprehension tasks. Conclusion: Print exposure and cortical volume atrophy may help explain variability in the language performance of nfvPPA individuals with similar age, education, disease duration, and cognitive ability.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Peristeri, Eleni UNSPECIFIED UNSPECIFIED UNSPECIFIED Messinis, Lambros UNSPECIFIED UNSPECIFIED UNSPECIFIED Kosmidis, Mary H. UNSPECIFIED UNSPECIFIED UNSPECIFIED Nasios, Grigorios UNSPECIFIED UNSPECIFIED UNSPECIFIED Mentis, Alexios-Fotios A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Siokas, Vasileios UNSPECIFIED UNSPECIFIED UNSPECIFIED Aloizou, Athina-Maria UNSPECIFIED UNSPECIFIED UNSPECIFIED Kotrotsios, Anastasios UNSPECIFIED UNSPECIFIED UNSPECIFIED Andreou, Maria UNSPECIFIED orcid.org/0000-0002-7867-3163 UNSPECIFIED Dardiotis, Efthimios UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-595593
DOI:	10.1097/WNN.0000000000000275
Journal or Publication Title:	Cogn. Behav. Neurol.
Volume:	34
Number:	3
Page Range:	S. 188 - 200
Date:	2021
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Place of Publication:	PHILADELPHIA
ISSN:	1543-3641
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SUPERIOR TEMPORAL GYRUS; PRINT EXPOSURE; WORKING-MEMORY; NORMATIVE DATA; COMPREHENSION; EDUCATION; PATTERNS; VARIANT; CORTEX; ADULTS Multiple languages Behavioral Sciences; Clinical Neurology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/59559