Universität zu Köln

Zou, Lai-Quan, Hummel, Thomas, Otte, Martin S., Bitter, Thomas, Besser, Gerold, Mueller, Christian A., Welge-Luessen, Antje, Bulut, Olcay Cem, Goektas, Oender, Negoias, Simona, Li, Shu-bin and Haehner, Antje (2021). Association between olfactory function and quality of life in patients with olfactory disorders: a multicenter study in over 760 participants. Rhinology, 59 (2). S. 164 - 173. UTRECHT: INT RHINOLOGIC SOC. ISSN 0300-0729

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Abstract

Background: This cross-sectional, multi-centric study aimed to investigate the differences in quality of life among patients with olfactory dysfunction (OD) of different origin, and to identify factors associated with olfactory-related quality of life (QOL). Methods: Seven hundred sixty-three adults were recruited from 8 Smell & Taste clinics in Germany, Switzerland, and Austria. Olfactory-related QOL was assessed by the Questionnaire of Olfactory Disorders (QOD). Olfactory function was assessed with the Sniffin' Sticks test; self-assessment was performed with visual analog scales. Results: Patients with post-infectious and post-traumatic OD showed poorer olfactory-related QOL than patients with sinonasal and idiopathic OD. The olfactory-related QOL was positively associated with the Sniffin' Sticks test score, self-assessed olfactory function, disease duration, and age, with younger olfactory dysfunction patients showing lower QOL. Female patients presented with poorer olfactory-related QOL. In addition, the results showed that self-assessment of olfactory function explained more of the variance in olfactory-related QOL than olfactory function evaluated by the Sniffin' Sticks test. Conclusions: In addition to the psychophysical testing results, several factors such as disease cause, disease duration, sex, or self-assessed olfactory dysfunction should be taken into account when assessing the individual severity of the smell loss.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Zou, Lai-Quan UNSPECIFIED UNSPECIFIED UNSPECIFIED Hummel, Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED Otte, Martin S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Bitter, Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED Besser, Gerold UNSPECIFIED UNSPECIFIED UNSPECIFIED Mueller, Christian A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Welge-Luessen, Antje UNSPECIFIED UNSPECIFIED UNSPECIFIED Bulut, Olcay Cem UNSPECIFIED UNSPECIFIED UNSPECIFIED Goektas, Oender UNSPECIFIED UNSPECIFIED UNSPECIFIED Negoias, Simona UNSPECIFIED UNSPECIFIED UNSPECIFIED Li, Shu-bin UNSPECIFIED UNSPECIFIED UNSPECIFIED Haehner, Antje UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-599716
DOI:	10.4193/Rhin20.403
Journal or Publication Title:	Rhinology
Volume:	59
Number:	2
Page Range:	S. 164 - 173
Date:	2021
Publisher:	INT RHINOLOGIC SOC
Place of Publication:	UTRECHT
ISSN:	0300-0729
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language IMPAIRMENT; DYSFUNCTION; PREVALENCE; SMELL Multiple languages Otorhinolaryngology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/59971