Universität zu Köln

Sibert, Nora Tabea, Dieng, Sebastian, Oesterle, Alisa, Feick, Guenter, Carl, Guenther, Steiner, Thomas, Minner, Joerg, Roghmann, Florian, Kaftan, Bjoern, Zengerling, Friedemann, Hinkel, Andreas, Beyer, Burkhard, Heidenreich, Axel, Harke, Nina, Brehmer, Bernhard, Pfitzenmaier, Jesco, Fichtner, Jan, Neisius, Andreas, Hammerer, Peter, Wesselmann, Simone and Kowalski, Christoph (2021). Psychometric validation of the German version of the EPIC-26 questionnaire for patients with localized and locally advanced prostate cancer. World J. Urol., 39 (1). S. 11 - 26. NEW YORK: SPRINGER. ISSN 1433-8726

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Abstract

Purpose For patients with prostate cancer, validated and reliable instruments are essential for measuring patient-reported outcomes. The aim of this study was to validate the German version of the widely established Expanded Prostate Cancer Index Composite with 26 items (EPIC-26). Methods A German translation of the original questionnaire was tested in 3094 patients with localized or locally advanced (any T, any N and M0) prostate cancer with treatment intent (including radical prostatectomy, brachytherapy, active surveillance, watchful waiting). They completed the EPIC-26 questionnaire before treatment. A total of 521 of them also completed a questionnaire 12 months afterward. Internal consistency, sensitivity to change, and construct validity were assessed. Results The internal consistency of all domains was sufficient (Cronbach's alpha between 0.64 and 0.93). Item-to-scale correlation coefficients showed acceptable associations between items and their domain score (all > 0.30), with the lowest scores for bloody stools (r = 0.37) and breast problems (r = 0.32). Confirmatory and exploratory factor analysis confirmed the five-dimension structure of the EPIC-26 (comparative fit index 0.95). Conclusions Psychometric evaluation suggests that the German version of the EPIC-26 is a well-constructed instrument for measuring patient-reported health-related symptoms in patients with prostate cancer.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Sibert, Nora Tabea UNSPECIFIED UNSPECIFIED UNSPECIFIED Dieng, Sebastian UNSPECIFIED UNSPECIFIED UNSPECIFIED Oesterle, Alisa UNSPECIFIED UNSPECIFIED UNSPECIFIED Feick, Guenter UNSPECIFIED UNSPECIFIED UNSPECIFIED Carl, Guenther UNSPECIFIED UNSPECIFIED UNSPECIFIED Steiner, Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED Minner, Joerg UNSPECIFIED UNSPECIFIED UNSPECIFIED Roghmann, Florian UNSPECIFIED UNSPECIFIED UNSPECIFIED Kaftan, Bjoern UNSPECIFIED UNSPECIFIED UNSPECIFIED Zengerling, Friedemann UNSPECIFIED UNSPECIFIED UNSPECIFIED Hinkel, Andreas UNSPECIFIED UNSPECIFIED UNSPECIFIED Beyer, Burkhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Heidenreich, Axel UNSPECIFIED UNSPECIFIED UNSPECIFIED Harke, Nina UNSPECIFIED UNSPECIFIED UNSPECIFIED Brehmer, Bernhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Pfitzenmaier, Jesco UNSPECIFIED UNSPECIFIED UNSPECIFIED Fichtner, Jan UNSPECIFIED UNSPECIFIED UNSPECIFIED Neisius, Andreas UNSPECIFIED UNSPECIFIED UNSPECIFIED Hammerer, Peter UNSPECIFIED UNSPECIFIED UNSPECIFIED Wesselmann, Simone UNSPECIFIED UNSPECIFIED UNSPECIFIED Kowalski, Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-601824
DOI:	10.1007/s00345-019-02949-7
Journal or Publication Title:	World J. Urol.
Volume:	39
Number:	1
Page Range:	S. 11 - 26
Date:	2021
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1433-8726
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language Urology & Nephrology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/60182