Universität zu Köln

Wimo, Anders, Belger, Mark, Bon, Jaka, Jessen, Frank, Dumas, Annette, Kramberger, Milica G., Jamilis, Laura, Johansson, Gunilla, Rodrigo Salas, Adrian, Gomez, Octavio Rodriguez, Sannemann, Lena, Stoekenbroek, Malou, Gurruchaga Telleria, Miren, Valero, Sergi, Vermunt, Lisa ORCID: 0000-0001-7420-6384, Waterink, Lisa, Winblad, Bengt, Jelle Visser, Peter, Zwan, Marissa and Boada, Merce (2021). A Cost-Consequence Analysis of Different Screening Procedures in Alzheimer's Disease: Results from the MOPEAD Project. J. Alzheimers Dis., 83 (3). S. 1149 - 1160. AMSTERDAM: IOS PRESS. ISSN 1875-8908

Full text not available from this repository.

Abstract

Background: For care planning and support, under-detection and late diagnosis of Alzheimer's disease (AD) is a great challenge. Models of Patient-Engagement for Alzheimer's Disease (MOPEAD) is an EU-funded project aiming at testing different strategies to improve this situation. Objective: To make a cost-consequence analysis of MOPEAD. Methods: Four screening strategies were tested in five countries (Germany, the Netherlands, Slovenia, Spain, and Sweden): 1) a web-approach; 2) Open-House initiative; 3) in primary care; and 4) by diabetes specialists. Persons-at-risk of AD in all strategies were offered referral to a hospital-based specialist. The primary health-economic outcome was the cost per true-positive case (TP) of AD from the screened population. Results: Of 2,847 screened persons, 1,121 screened positive (39%), 402 were evaluated at memory clinics (14%), and 236 got an AD diagnosis (8%). The cost per TP of those screened was (sic)3,115 with the web-approach, (sic)2,722 with the Open-House, (sic)1,530 in primary care, and (sic)1,190 by diabetes specialists. Sensitivity analyses that more likely reflect the real-world situation confirmed the results. The number-needed-to-screen was 30 with the web-approach, 8 with the Open-House and primary care, and 6 with the diabetes specialists. There were country differences in terms of screening rates, referrals to memory clinics, staff-types involved, and costs per TP. Conclusion: In primary care and by the diabetes specialist, the costs per TP/screened population were lowest, but the capacity of such settings to identify cases with AD-risk must be discussed. Hence new diagnostic strategies such as web-solutions and Open-House initiatives may be valuable after modifications.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Wimo, Anders UNSPECIFIED UNSPECIFIED UNSPECIFIED Belger, Mark UNSPECIFIED UNSPECIFIED UNSPECIFIED Bon, Jaka UNSPECIFIED UNSPECIFIED UNSPECIFIED Jessen, Frank UNSPECIFIED UNSPECIFIED UNSPECIFIED Dumas, Annette UNSPECIFIED UNSPECIFIED UNSPECIFIED Kramberger, Milica G. UNSPECIFIED UNSPECIFIED UNSPECIFIED Jamilis, Laura UNSPECIFIED UNSPECIFIED UNSPECIFIED Johansson, Gunilla UNSPECIFIED UNSPECIFIED UNSPECIFIED Rodrigo Salas, Adrian UNSPECIFIED UNSPECIFIED UNSPECIFIED Gomez, Octavio Rodriguez UNSPECIFIED UNSPECIFIED UNSPECIFIED Sannemann, Lena UNSPECIFIED UNSPECIFIED UNSPECIFIED Stoekenbroek, Malou UNSPECIFIED UNSPECIFIED UNSPECIFIED Gurruchaga Telleria, Miren UNSPECIFIED UNSPECIFIED UNSPECIFIED Valero, Sergi UNSPECIFIED UNSPECIFIED UNSPECIFIED Vermunt, Lisa UNSPECIFIED orcid.org/0000-0001-7420-6384 UNSPECIFIED Waterink, Lisa UNSPECIFIED UNSPECIFIED UNSPECIFIED Winblad, Bengt UNSPECIFIED UNSPECIFIED UNSPECIFIED Jelle Visser, Peter UNSPECIFIED UNSPECIFIED UNSPECIFIED Zwan, Marissa UNSPECIFIED UNSPECIFIED UNSPECIFIED Boada, Merce UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-602237
DOI:	10.3233/JAD-210303
Journal or Publication Title:	J. Alzheimers Dis.
Volume:	83
Number:	3
Page Range:	S. 1149 - 1160
Date:	2021
Publisher:	IOS PRESS
Place of Publication:	AMSTERDAM
ISSN:	1875-8908
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language DEMENTIA; CARE; PEOPLE Multiple languages Neurosciences Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/60223