Rhiem, Kerstin, Auber, Bernd, Briest, Susanne, Dikow, Nicola, Ditsch, Nina, Dragicevic, Neda, Grill, Sabine, Hahnen, Eric, Horvath, Judit, Jaeger, Bernadette, Kast, Karin, Kiechle, Marion, Leinert, Elena, Morlot, Susanne, Puesken, Michael, Schaefer, Dieter, Schott, Sarah, Schroeder, Christopher, Siebers-Renelt, Ulrike, Solbach, Christine, Weber-Lassalle, Nana, Witzel, Isabell, Zeder-Goess, Christine and Schmutzler, Rita K. . Consensus Recommendations of the German Consortium for Hereditary Breast and Ovarian Cancer. Breast Care. BASEL: KARGER. ISSN 1661-3805

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Abstract

Background: The German Consortium for Hereditary Breast and Ovarian Cancer (GC-HBOC) has established a multigene panel (TruRisk (R)) for the analysis of risk genes for familial breast and ovarian cancer. Summary: An interdisciplinary team of experts from the GC-HBOC has evaluated the available data on risk modification in the presence of pathogenic mutations in these genes based on a structured literature search and through a formal consensus process. Key Messages: The goal of this work is to better assess individual disease risk and, on this basis, to derive clinical recommendations for patient counseling and care at the centers of the GC-HBOC from the initial consultation prior to genetic testing to the use of individual risk-adapted preventive/therapeutic measures.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Rhiem, KerstinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Auber, BerndUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Briest, SusanneUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dikow, NicolaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ditsch, NinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dragicevic, NedaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Grill, SabineUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hahnen, EricUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Horvath, JuditUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jaeger, BernadetteUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kast, KarinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kiechle, MarionUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Leinert, ElenaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Morlot, SusanneUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Puesken, MichaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schaefer, DieterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schott, SarahUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schroeder, ChristopherUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Siebers-Renelt, UlrikeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Solbach, ChristineUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Weber-Lassalle, NanaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Witzel, IsabellUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Zeder-Goess, ChristineUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schmutzler, Rita K.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-603512
DOI: 10.1159/000516376
Journal or Publication Title: Breast Care
Publisher: KARGER
Place of Publication: BASEL
ISSN: 1661-3805
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
LI-FRAUMENI SYNDROME; GERMLINE MUTATIONS; TP53; FREQUENCY; RISKS; SUSCEPTIBILITY; VARIANTS; BRCA2; CHEK2; GUIDELINESMultiple languages
Oncology; Obstetrics & GynecologyMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/60351

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