Universität zu Köln

Schlereth, Simona L., Hos, Deniz, Matthaei, Mario, Hamrah, Pedram, Schmetterer, Leopold, O'Leary, Olivia, Ullmer, Christoph, Horstmann, Jens, Bock, Felix, Wacker, Katrin ORCID: 0000-0002-4164-561X, Schroder, Hannes, Notara, Maria, Haagdorens, Michel, Nuijts, Rudy M. M. A., Dunker, Suryan, Dickman, Mor ORCID: 0000-0001-9545-343X, Fauser, Sascha, Scholl, Hendrik P. N., Wheeler-Schilling, Thomas and Cursiefen, Claus (2021). New Technologies in Clinical Trials in Corneal Diseases and Limbal Stem Cell Deficiency: Review from the European Vision Institute Special Interest Focus Group Meeting. Ophthalmic Res., 64 (2). S. 145 - 168. BASEL: KARGER. ISSN 1423-0259

Full text not available from this repository.

Abstract

To discuss and evaluate new technologies for a better diagnosis of corneal diseases and limbal stem cell deficiency, the outcomes of a consensus process within the European Vision Institute (and of a workshop at the University of Cologne) are outlined. Various technologies are presented and analyzed for their potential clinical use also in defining new end points in clinical trials. The disease areas which are discussed comprise dry eye and ocular surface inflammation, imaging, and corneal neovascularization and corneal grafting/stem cell and cell transplantation. The unmet needs in the abovementioned disease areas are discussed, and realistically achievable new technologies for better diagnosis and use in clinical trials are outlined. To sum up, it can be said that there are several new technologies that can improve current diagnostics in the field of ophthalmology in the near future and will have impact on clinical trial end point design.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schlereth, Simona L. UNSPECIFIED UNSPECIFIED UNSPECIFIED Hos, Deniz UNSPECIFIED UNSPECIFIED UNSPECIFIED Matthaei, Mario UNSPECIFIED UNSPECIFIED UNSPECIFIED Hamrah, Pedram UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmetterer, Leopold UNSPECIFIED UNSPECIFIED UNSPECIFIED O'Leary, Olivia UNSPECIFIED UNSPECIFIED UNSPECIFIED Ullmer, Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED Horstmann, Jens UNSPECIFIED UNSPECIFIED UNSPECIFIED Bock, Felix UNSPECIFIED UNSPECIFIED UNSPECIFIED Wacker, Katrin UNSPECIFIED orcid.org/0000-0002-4164-561X UNSPECIFIED Schroder, Hannes UNSPECIFIED UNSPECIFIED UNSPECIFIED Notara, Maria UNSPECIFIED UNSPECIFIED UNSPECIFIED Haagdorens, Michel UNSPECIFIED UNSPECIFIED UNSPECIFIED Nuijts, Rudy M. M. A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Dunker, Suryan UNSPECIFIED UNSPECIFIED UNSPECIFIED Dickman, Mor UNSPECIFIED orcid.org/0000-0001-9545-343X UNSPECIFIED Fauser, Sascha UNSPECIFIED UNSPECIFIED UNSPECIFIED Scholl, Hendrik P. N. UNSPECIFIED UNSPECIFIED UNSPECIFIED Wheeler-Schilling, Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED Cursiefen, Claus UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-604619
DOI:	10.1159/000509954
Journal or Publication Title:	Ophthalmic Res.
Volume:	64
Number:	2
Page Range:	S. 145 - 168
Date:	2021
Publisher:	KARGER
Place of Publication:	BASEL
ISSN:	1423-0259
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language OPTICAL COHERENCE TOMOGRAPHY; VIVO CONFOCAL MICROSCOPY; TEAR FILM THICKNESS; MEMBRANE ENDOTHELIAL KERATOPLASTY; DRY EYE DISEASE; VERSUS-HOST-DISEASE; ANTERIOR LAMELLAR KERATOPLASTY; MEIBOMIAN GLAND DYSFUNCTION; IN-VIVO; OCULAR SURFACE Multiple languages Ophthalmology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/60461