Randerath, Winfried ORCID: 0000-0002-5010-8461, Verbraecken, Johan ORCID: 0000-0002-6087-678X, de Raaff, Christel A. L., Hedner, Jan, Herkenrath, Simon, Hohenhorst, Winfried, Jakob, Tina, Marrone, Oreste, Marklund, Marie, McNicholas, Walter T., Morgan, Rebecca L., Pepin, Jean-Louis, Schiza, Sofia, Skoetz, Nicole, Smyth, Dan, Steier, Jorg, Tonia, Thomy, Trzepizur, Wojciech, Van Mechelen, Piet-Heijn and Wijkstra, Peter (2021). European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea. Eur. Respir. Rev., 30 (162). SHEFFIELD: EUROPEAN RESPIRATORY SOC JOURNALS LTD. ISSN 1600-0617

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Abstract

Treatment of obstructive sleep apnoea (OSA) in adults is evolving, as new therapies have been explored and introduced in clinical practice, while other approaches have been refined or reconsidered. In this European Respiratory Society (ERS) guideline on non-continuous positive airway pressure (CPAP) therapies for OSA, we present recommendations determined by a systematic review of the literature. It is an update of the 2011 ERS statement on non-CPAP therapies, advanced into a clinical guideline. A multidisciplinary group of experts, including pulmonary, surgical, dentistry and ear-nose-throat specialists, methodologists and patient representatives considered the most relevant clinical questions (for both clinicians and patients) relating to the management of OSA. Eight key clinical questions were generated and a systematic review was conducted to identify published randomised clinical trials that answered these questions. We used the GRADE (Grading of Recommendations Assessment, Development and Evaluation) approach to assess the quality of the evidence and the strength of recommendations. The resulting guideline addresses gastric bypass surgery, custom-made dual-block mandibular advancement devices, hypoglossal nerve stimulation, myofunctional therapy, maxillo-mandibular osteotomy, carbonic anhydrase inhibitors and positional therapy. These recommendations can be used to benchmark quality of care for people with OSA across Europe and to improve outcomes.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Randerath, WinfriedUNSPECIFIEDorcid.org/0000-0002-5010-8461UNSPECIFIED
Verbraecken, JohanUNSPECIFIEDorcid.org/0000-0002-6087-678XUNSPECIFIED
de Raaff, Christel A. L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hedner, JanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Herkenrath, SimonUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hohenhorst, WinfriedUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jakob, TinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Marrone, OresteUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Marklund, MarieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
McNicholas, Walter T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Morgan, Rebecca L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pepin, Jean-LouisUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schiza, SofiaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Skoetz, NicoleUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Smyth, DanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Steier, JorgUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tonia, ThomyUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Trzepizur, WojciechUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Van Mechelen, Piet-HeijnUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wijkstra, PeterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-605172
DOI: 10.1183/16000617.0200-2021
Journal or Publication Title: Eur. Respir. Rev.
Volume: 30
Number: 162
Date: 2021
Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD
Place of Publication: SHEFFIELD
ISSN: 1600-0617
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
POSITIVE AIRWAY PRESSURE; ORAL APPLIANCE THERAPY; MANDIBULAR ADVANCEMENT DEVICE; PLACEBO-CONTROLLED TRIAL; TENNIS BALL TECHNIQUE; QUALITY-OF-LIFE; OROPHARYNGEAL EXERCISES; HEALTH OUTCOMES; DOUBLE-BLIND; FOLLOW-UPMultiple languages
Respiratory SystemMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/60517

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