Keller, Josbert J., Ooijevaar, Rogier E., Hvas, Christian L., Terveer, Elisabeth M., Lieberknecht, Simone C., Hogenauer, Christoph ORCID: 0000-0003-4566-0806, Arkkila, Perttu, Sokol, Harry, Gridnyev, Oleksiy ORCID: 0000-0003-4716-3520, Megraud, Francis ORCID: 0000-0002-2481-1612, Kump, Patrizia K., Nakov, Radislav, Goldenberg, Simon D., Satokari, Reetta, Tkatch, Sergiy, Sanguinetti, Maurizio ORCID: 0000-0002-9780-7059, Cammarota, Giovanni ORCID: 0000-0002-3626-6148, Dorofeev, Andrey, Gubska, Olena, Laniro, Gianluca, Mattila, Eero, Arasaradnam, Ramesh P., Sarin, Shiv K., Sood, Ajit, Putignani, Lorenza ORCID: 0000-0003-0134-2830, Alric, Laurent, Baunwall, Simon M. D., Kupcinskas, Juozas, Link, Alexander ORCID: 0000-0002-9514-4562, Goorhuis, Abraham G., Verspaget, Hein W., Ponsioen, Cyriel, Hold, Georgina L., Tilg, Herbert, Kassam, Zain, Kuijper, Ed J., Gasbarrini, Antonio ORCID: 0000-0003-4863-6924, Mulder, Chris J. J., Williams, Horace R. T. and Vehreschild, Maria J. G. T. (2021). A standardised model for stool banking for faecal microbiota transplantation: a consensus report from a multidisciplinary UEG working group. United European Gastroenterol. J., 9 (2). S. 229 - 248. THOUSAND OAKS: SAGE PUBLICATIONS INC. ISSN 2050-6414

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Abstract

Background Faecal microbiota transplantation is an emerging therapeutic option, particularly for the treatment of recurrent Clostridioides difficile infection. Stool banks that organise recruitment and screening of faeces donors are being embedded within the regulatory frameworks described in the European Union Tissue and Cells Directive and the technical guide to the quality and safety of tissue and cells for human application, published by the European Council. Objective Several European and international consensus statements concerning faecal microbiota transplantation have been issued. While these documents provide overall guidance, we aim to provide a detailed description of all processes that relate to the collection, handling and clinical application of human donor stool in this document. Methods Collaborative subgroups of experts on stool banking drafted concepts for all domains pertaining to stool banking. During a working group meeting in the United European Gastroenterology Week 2019 in Barcelona, these concepts were discussed and finalised to be included in our overall guidance document about faecal microbiota transplantation. Results A guidance document for all domains pertaining to stool banking was created. This document includes standard operating manuals for several processes involved with stool banking, such as handling of donor material, storage and donor screening. Conclusion The implementation of faecal microbiota transplantation by stool banks in concordance with our guidance document will enable quality assurance and guarantee the availability of donor faeces preparations for patients.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Keller, Josbert J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ooijevaar, Rogier E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hvas, Christian L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Terveer, Elisabeth M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lieberknecht, Simone C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hogenauer, ChristophUNSPECIFIEDorcid.org/0000-0003-4566-0806UNSPECIFIED
Arkkila, PerttuUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sokol, HarryUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gridnyev, OleksiyUNSPECIFIEDorcid.org/0000-0003-4716-3520UNSPECIFIED
Megraud, FrancisUNSPECIFIEDorcid.org/0000-0002-2481-1612UNSPECIFIED
Kump, Patrizia K.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Nakov, RadislavUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Goldenberg, Simon D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Satokari, ReettaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tkatch, SergiyUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sanguinetti, MaurizioUNSPECIFIEDorcid.org/0000-0002-9780-7059UNSPECIFIED
Cammarota, GiovanniUNSPECIFIEDorcid.org/0000-0002-3626-6148UNSPECIFIED
Dorofeev, AndreyUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gubska, OlenaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Laniro, GianlucaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mattila, EeroUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Arasaradnam, Ramesh P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sarin, Shiv K.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sood, AjitUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Putignani, LorenzaUNSPECIFIEDorcid.org/0000-0003-0134-2830UNSPECIFIED
Alric, LaurentUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Baunwall, Simon M. D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kupcinskas, JuozasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Link, AlexanderUNSPECIFIEDorcid.org/0000-0002-9514-4562UNSPECIFIED
Goorhuis, Abraham G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Verspaget, Hein W.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ponsioen, CyrielUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hold, Georgina L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tilg, HerbertUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kassam, ZainUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kuijper, Ed J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gasbarrini, AntonioUNSPECIFIEDorcid.org/0000-0003-4863-6924UNSPECIFIED
Mulder, Chris J. J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Williams, Horace R. T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Vehreschild, Maria J. G. T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-607586
DOI: 10.1177/2050640620967898
Journal or Publication Title: United European Gastroenterol. J.
Volume: 9
Number: 2
Page Range: S. 229 - 248
Date: 2021
Publisher: SAGE PUBLICATIONS INC
Place of Publication: THOUSAND OAKS
ISSN: 2050-6414
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
Gastroenterology & HepatologyMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/60758

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