Universität zu Köln

Fassunke, Jana, Engels, Marianne, Meemboor, Sonja and Buettner, Reinhard (2022). Cytopathology and molecular diagnostics of non-small cell lung cancer (NSCLC). Innere Med., 63 (7). S. 694 - 700. Berlin: SPRINGER MEDIZIN. ISSN 2731-7099

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Abstract

Cytological specimens from endobronchial aspirates and pleural effusions are frequently used materials in the diagnostics of non-small cell lung cancer (NSCLC). In the same way as histological samples from endobronchial and transbronchial biopsy material or computed tomography (CT)-guided needle biopsies, cytological specimens are eminently suitable for molecular and immunohistological biomarker diagnostics of NSCLC, provided optimal techniques and clear diagnostic algorithms are employed. This article presents the typical processing techniques and a scheme for biomarker analytics and discusses an optimal approach for comprehensive diagnostics of NSCLC. When cytological specimens are processed and used in this way, the analytics are equivalent to those from histopathological specimens. For a detailed and advanced description of cytological and molecular techniques on cytological specimens the reader is referred to our own review articles.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Fassunke, Jana UNSPECIFIED UNSPECIFIED UNSPECIFIED Engels, Marianne UNSPECIFIED UNSPECIFIED UNSPECIFIED Meemboor, Sonja UNSPECIFIED UNSPECIFIED UNSPECIFIED Buettner, Reinhard UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-657757
DOI:	10.1007/s00108-022-01365-1
Journal or Publication Title:	Innere Med.
Volume:	63
Number:	7
Page Range:	S. 694 - 700
Date:	2022
Publisher:	SPRINGER MEDIZIN
Place of Publication:	Berlin
ISSN:	2731-7099
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SPECIMENS Multiple languages Medicine, General & Internal Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/65775