Universität zu Köln

Merkle-Storms, Julia, Djordjevic, Ilija ORCID: 0000-0002-5810-8626, Gaisendrees, Christopher, Ivanov, Borko ORCID: 0000-0001-8052-8232, Weber, Carolyn, Krasivskyi, Ihor ORCID: 0000-0003-0573-8218, Avgeridou, Soi, Mihaylova, Mariya, Mader, Navid, Kuhn-Regnier, Ferdinand, Sabashnikov, Anton and Wahlers, Thorsten (2023). Impact of postoperative acute kidney injury on short-term outcomes of patients with Bentall surgery for any reason. Perfusion-UK, 38 (3). S. 631 - 637. LONDON: SAGE PUBLICATIONS LTD. ISSN 1477-111X

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Abstract

Background Acute kidney injury (AKI) after cardiac surgery is a well-known risk factor for increased postoperative mortality and morbidity. The effect of postoperative developed AKI on postoperative outcomes in patients after Bentall procedure has been incompletely investigated. The present study was dedicated to assessing the impact of postoperative AKI on morbidity and 30-day mortality in this specific cohort. Methods In a retrospective observational study, we investigated 249 patients undergoing Bentall procedure from January 2014 to March 2018 at the University Hospital of Cologne, Germany. After excluding patients with preoperative renal impairment, patients were divided into an AKI group (n = 88) and a non-AKI group (n = 97). Postoperative outcomes and 30-day mortality were analyzed using univariate regression analysis. AKI was defined by AKIN criteria. Results Mortality during ICU and hospital stay, as well as 30-day mortality, was significantly higher in the AKI group (all p < 0.001). Patients with postoperative developed AKI revealed 9.3-fold higher odds for ICU mortality and 6.7-fold higher odds for 30-day mortality in comparison to non-AKI group (all p < 0.004) as well as 4.5-fold higher odds for stroke. Coronary artery bypass time, as well as cross-clamp time, were similarly distributed between groups, whereas incidences of postoperative bleeding, myocardial infarction, and need for rethoracotomy occurred significantly more often in patients with postoperatively developed AKI (all p < 0.04). Conclusion Patients undergoing Bentall surgery who postoperatively developed AKI showed significantly higher morbidity and mortality. AKI points out to be an early predictor for poor outcomes. Thus, as a consequence, patients with postoperatively developed AKI should be highly monitored for immediate intervention.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Merkle-Storms, Julia UNSPECIFIED UNSPECIFIED UNSPECIFIED Djordjevic, Ilija UNSPECIFIED orcid.org/0000-0002-5810-8626 UNSPECIFIED Gaisendrees, Christopher UNSPECIFIED UNSPECIFIED UNSPECIFIED Ivanov, Borko UNSPECIFIED orcid.org/0000-0001-8052-8232 UNSPECIFIED Weber, Carolyn UNSPECIFIED UNSPECIFIED UNSPECIFIED Krasivskyi, Ihor UNSPECIFIED orcid.org/0000-0003-0573-8218 UNSPECIFIED Avgeridou, Soi UNSPECIFIED UNSPECIFIED UNSPECIFIED Mihaylova, Mariya UNSPECIFIED UNSPECIFIED UNSPECIFIED Mader, Navid UNSPECIFIED UNSPECIFIED UNSPECIFIED Kuhn-Regnier, Ferdinand UNSPECIFIED UNSPECIFIED UNSPECIFIED Sabashnikov, Anton UNSPECIFIED UNSPECIFIED UNSPECIFIED Wahlers, Thorsten UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-659355
DOI:	10.1177/02676591211073865
Journal or Publication Title:	Perfusion-UK
Volume:	38
Number:	3
Page Range:	S. 631 - 637
Date:	2023
Publisher:	SAGE PUBLICATIONS LTD
Place of Publication:	LONDON
ISSN:	1477-111X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CARDIAC-SURGERY Multiple languages Cardiac & Cardiovascular Systems; Peripheral Vascular Disease Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/65935