Universität zu Köln

Scheffler, Matthias, Michels, Sebastian and Nogova, Lucia (2022). Targeted treatment of non-small cell lung cancer. Innere Med., 63 (7). S. 700 - 709. Berlin: SPRINGER MEDIZIN. ISSN 2731-7099

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Abstract

Non-small cell lung cancer (NSCLC) has made a remarkable development in recent decades with respect to its perception. In the late 1990s it was the problem child as the main cause of cancer with increasing tendencies, especially in women and with a pronounced stigmatization. It is now the role model as a biologically rational targeted treatment based on molecular dependencies of the tumor with a vast improvement of the traditionally poor survival times. Molecular tumor boards have long followed the NSCLC example in the assessment of targeted treatment approaches for other tumor entities. This review article gives an overview of the current possibilities for targeted treatment of NSCLC, which nowadays are applicable for nearly one third of all patients with NSCLC.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Scheffler, Matthias UNSPECIFIED UNSPECIFIED UNSPECIFIED Michels, Sebastian UNSPECIFIED UNSPECIFIED UNSPECIFIED Nogova, Lucia UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-659825
DOI:	10.1007/s00108-022-01372-2
Journal or Publication Title:	Innere Med.
Volume:	63
Number:	7
Page Range:	S. 700 - 709
Date:	2022
Publisher:	SPRINGER MEDIZIN
Place of Publication:	Berlin
ISSN:	2731-7099
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language OPEN-LABEL; ACQUIRED-RESISTANCE; INTEGRATED ANALYSIS; 1ST-LINE TREATMENT; EGFR MUTATIONS; CHEMOTHERAPY; MULTICENTER; CRIZOTINIB; PHASE-3; EFFICACY Multiple languages Medicine, General & Internal Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/65982