Universität zu Köln

Krasivskyi, Ihor ORCID: 0000-0003-0573-8218, Ivanov, Borko, Eghbalzadeh, Kaveh, Fehlau, Frederike, Gerfer, Stephen, Grossmann, Clara, Elderia, Ahmed ORCID: 0000-0002-6859-5384, Sabashnikov, Anton, Rahmanian, Parwis Baradaran, Mader, Navid, Djordjevic, Ilija ORCID: 0000-0002-5810-8626 and Wahlers, Thorsten ORCID: 0000-0002-8437-4119 (2022). Sex-Associated Differences in Short-Term Outcomes in Patients with Deep Sternal Wound Infection after Open-Heart Surgery. J. Clin. Med., 11 (24). BASEL: MDPI. ISSN 2077-0383

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Abstract

Deep sternal wound infection (DSWI) is a feared complication after cardiac surgery. The impact of sex-related differences on wound infection prevalence is poorly understood. Our aim was to evaluate the effect of sex on short-term outcomes in patients with DSWI after open-heart surgery. The study was a retrospective cohort study. A total of 217 patients with DSWI were identified and retrospectively analyzed using our institutional database. Patients were divided into two groups: males (n = 150) and females (n = 67). This study also includes a propensity score based matching (PSM) analysis (male group (n = 62) and female group (n = 62)) to examine the unequal groups. Mean age (p = 0.088) and mean body mass index (BMI) (p = 0.905) did not significantly differ between both groups. Vacuum assisted closure (VAC) therapy was performed among most patients (82.3% (male group) vs. 83.9% (female group), p = 0.432). The most commonly isolated bacteria from the wounds were Staphylococcus epidermidis and Staphylococcus aureus in both groups. Acute renal failure was significantly higher (p = 0.010) in the male group compared to the female group. However, dialysis rate did not significantly differ (p = 0.491) between male and female groups. Further secondary outcomes showed no major differences between the groups. Likewise, in-hospital mortality rate did not differ significantly (p = 0.680) between both groups. Based on our data, sex has no impact on deep wound infection prevalence after cardiac surgery.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Krasivskyi, Ihor UNSPECIFIED orcid.org/0000-0003-0573-8218 UNSPECIFIED Ivanov, Borko UNSPECIFIED UNSPECIFIED UNSPECIFIED Eghbalzadeh, Kaveh UNSPECIFIED UNSPECIFIED UNSPECIFIED Fehlau, Frederike UNSPECIFIED UNSPECIFIED UNSPECIFIED Gerfer, Stephen UNSPECIFIED UNSPECIFIED UNSPECIFIED Grossmann, Clara UNSPECIFIED UNSPECIFIED UNSPECIFIED Elderia, Ahmed UNSPECIFIED orcid.org/0000-0002-6859-5384 UNSPECIFIED Sabashnikov, Anton UNSPECIFIED UNSPECIFIED UNSPECIFIED Rahmanian, Parwis Baradaran UNSPECIFIED UNSPECIFIED UNSPECIFIED Mader, Navid UNSPECIFIED UNSPECIFIED UNSPECIFIED Djordjevic, Ilija UNSPECIFIED orcid.org/0000-0002-5810-8626 UNSPECIFIED Wahlers, Thorsten UNSPECIFIED orcid.org/0000-0002-8437-4119 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-662602
DOI:	10.3390/jcm11247510
Journal or Publication Title:	J. Clin. Med.
Volume:	11
Number:	24
Date:	2022
Publisher:	MDPI
Place of Publication:	BASEL
ISSN:	2077-0383
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language BYPASS GRAFT-SURGERY; VACUUM-ASSISTED CLOSURE; RISK-FACTOR-ANALYSIS; GENDER-DIFFERENCES; CARDIAC-SURGERY; ARTERY; MEDIASTINITIS; MORTALITY; WOMEN; SURVIVAL Multiple languages Medicine, General & Internal Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/66260