Universität zu Köln

Al Saleh, Helal and Moesges, Ralph (2022). MicroCrystalline Tyrosine-adsorbed immunotherapy. Curr. Opin. Allergy Clin. Immunol., 22 (6). S. 413 - 421. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1473-6322

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Abstract

Purpose of review The purpose of this article is to provide an overview of the literature pertaining to the use of MicroCrystalline Tyrosine (MCT) in the immunotherapy with an emphasis on recent developments. Recent findings In addition to significant effectiveness and safety profiles, additional aspects of interest such as booster immunotherapy concepts, sustained clinical effects, long-term efficacy and disease-modifying effects are being focused on in the recently published studies. The depot adjuvant MCT also shows potential in promising disease-challenge models such as for malaria and melanoma. MCT-adsorbed immunotherapy products have been shown to provide convincing overall safety, tolerability and efficacy outcomes, as well in vulnerable groups such as children and asthmatic patients.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Al Saleh, Helal UNSPECIFIED UNSPECIFIED UNSPECIFIED Moesges, Ralph UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-662808
DOI:	10.1097/ACI.0000000000000859
Journal or Publication Title:	Curr. Opin. Allergy Clin. Immunol.
Volume:	22
Number:	6
Page Range:	S. 413 - 421
Date:	2022
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Place of Publication:	PHILADELPHIA
ISSN:	1473-6322
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language MONOPHOSPHORYL-LIPID-A; ADVERSE SYSTEMIC REACTIONS; SHORT-TERM IMMUNOTHERAPY; ALLERGEN IMMUNOTHERAPY; SUBCUTANEOUS IMMUNOTHERAPY; POLLEN ALLERGOIDS; EUROPEAN SURVEY; ADJUVANT; RHINOCONJUNCTIVITIS; EFFICACY Multiple languages Allergy; Immunology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/66280